Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL46132 | 0.83 | GRM5 (0.37) | HPGDMAOBPTPN1 | |
| SCHEMBL2759748 | 0.78 | HTT (0.38) | GAAHTTNPSR1 | |
| SCHEMBL13366865 | 0.74 | HTR2A (0.33) | HTT | |
| SCHEMBL2759768 | 0.72 | ALDH1A1 (0.34) | GAA | |
| SCHEMBL46110 | 0.71 | LMNA (0.35) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL37409 | 0.71 | GRM5 (0.34) | MAOBMAOAHTTNPSR1 | |
| SCHEMBL2759755 | 0.70 | MAPK1 (0.36) | GAAHTTNPSR1 | |
| SCHEMBL2759757 | 0.69 | HTT (0.33) | GAAHTTNPSR1 | |
| SCHEMBL2759794 | 0.69 | ALDH1A1 (0.37) | HTT | |
| SCHEMBL2759787 | 0.68 | GAA (0.34) | GAAHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2575469-B1 | PESTICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-03-14 | — | — | EP | disclosed |
| US-9771365-B2 | Spiroheterocyclic N-oxypiperidines as pesticides | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-26 | — | — | US | disclosed |
| US-9771365-B2 | Spiroheterocyclic N-oxypiperidines as pesticides | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-26 | — | — | US | disclosed |
| EP-2575472-B1 | METHOD OF CONTROLLING NEONICOTINOID RESISTANT HEMIPTERA USING SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-07-19 | — | — | EP | disclosed |
| US-9485989-B2 | Method of controlling neonicotinoid resistant hemiptera | SYNGENTA PARTICIPATIONS AG (CH) | 2016-11-08 | — | — | US | disclosed |
| US-9485989-B2 | Method of controlling neonicotinoid resistant hemiptera | SYNGENTA PARTICIPATIONS AG (CH) | 2016-11-08 | — | — | US | disclosed |
| US-9462808-B2 | Pesticidal compositions | SYNGENTA PARTICIPANTS AG (CH) | 2016-10-11 | — | — | US | disclosed |
| US-9462808-B2 | Pesticidal compositions | SYNGENTA PARTICIPANTS AG (CH) | 2016-10-11 | — | — | US | disclosed |
| EP-2575449-B1 | PESTICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-04-27 | — | — | EP | disclosed |
| US-20150259345-A1 | SPIROHETEROCYCLIC N-OXYPIPERIDINES AS PESTICIDES | SYNGENTA LIMITED (GB) | 2015-09-17 | — | — | US | disclosed |
| US-20120004105-A1 | HERBICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION LLC (US) | 2012-01-05 | — | — | US | disclosed |
| US-20120004105-A1 | HERBICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION LLC (US) | 2012-01-05 | — | — | US | disclosed |
| WO-2011151249-A2 | METHOD OF CONTROLLING NEONICOTINOID RESISTANT HEMIPTERA | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-08 | — | — | WO | disclosed |
| US-20110301031-A1 | SPIROHETEROCYCLIC N-OXYPIPERIDINES AS PESTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2011-12-08 | — | — | US | disclosed |
| US-20110301031-A1 | SPIROHETEROCYCLIC N-OXYPIPERIDINES AS PESTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2011-12-08 | — | — | US | disclosed |
| WO-2011151247-A2 | PESTICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-08 | — | — | WO | disclosed |
| WO-2011151248-A1 | PESTICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-08 | — | — | WO | disclosed |
| WO-2011151194-A1 | 1, 8 -DIAZASPIRO [4.5] DECANE- 2, 4 -DIONE DERIVATIVES USEFUL AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-08 | — | — | WO | disclosed |
| WO-2010066780-A1 | SPIROHETEROCYCLIC N-OXYPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-06-17 | — | — | WO | disclosed |
| WO-2010052161-A2 | HERBICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004105-A1 | HERBICIDAL COMPOSITIONS | DDT, CAT, HDHD5 | CXCR2 2049/4885CNR1 3640/4885PSEN1 4354/4885 |
| US-20110301031-A1 | SPIROHETEROCYCLIC N-OXYPIPERIDINES AS PESTICIDES | DDT, THOP1, KCNH1 | CXCR2 1228/4885CNR1 198/4885PSEN1 2057/4885 |
| US-20150259345-A1 | SPIROHETEROCYCLIC N-OXYPIPERIDINES AS PESTICIDES | DDT, THOP1, KCNH1 | CXCR2 1196/4885CNR1 214/4885PSEN1 2152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.