Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GRN | P28799 | 2/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TPMT | P51580 | 1/20 | 0.32 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27406402 | 0.87 | ALDH1A1 (0.39) | ALDH1A1HPGDL3MBTL1LMNAGRN | |
| SCHEMBL4614625 | 0.84 | L3MBTL1 (0.42) | ALDH1A1HPGDL3MBTL1LMNAGRN | |
| Hydrochloric Acid SCHEMBL4612487 | 0.84 | ALDH1A1 (0.40) | ALDH1A1HPGDL3MBTL1GRNSORT1 | |
| SCHEMBL819824 | 0.76 | GLS (0.46) | ALDH1A1HPGDLMNAMEN1MAPT | |
| SCHEMBL16759671 | 0.73 | PYGL (0.39) | ALDH1A1HPGDL3MBTL1LMNAMAPT | |
| SCHEMBL16759074 | 0.71 | SLC6A2 (0.36) | ALDH1A1HPGDMAPTSLC6A2SLC6A4 | |
| SCHEMBL16770966 | 0.71 | SLC6A2 (0.36) | ALDH1A1HPGDLMNAGRNSORT1 | |
| SCHEMBL17071865 | 0.71 | SLC6A2 (0.36) | ALDH1A1HPGDLMNAGRNSORT1 | |
| SCHEMBL16770758 | 0.71 | SLC6A2 (0.36) | ALDH1A1HPGDLMNAGRNSORT1 | |
| SCHEMBL27406403 | 0.69 | ALDH1A1 (0.33) | ALDH1A1HPGDL3MBTL1GRNSORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567480-B1 | N-ALKYNYL-2-(SUBSTITUTED PHENOXY) ALKYLAMIDES AND THEIR USE AS FUNGICIDES | SYNGENTA LTD (GB) | 2008-03-12 | — | — | EP | disclosed |
| US-7271130-B2 | N-alkynyl-2-(substituted phenoxy) alkylamides and their use as fungicides | SYNGENTA LIMITED (GB) | 2007-09-18 | — | — | US | disclosed |
| US-20060194763-A1 | N-alkynyl-2-(substituted phenoxy) alkylamides and their use as fungicides | SYNGENTA LIMITED (GB) | 2006-08-31 | — | — | US | disclosed |
| EP-1567480-A1 | N-ALKYNYL-2-(SUBSTITUTED PHENOXY) ALKYLAMIDES AND THEIR USE AS FUNGICIDES | Syngenta Limited (GB) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004048316-A1 | N-ALKYNYL-2- (SUBSTITUTED PHENOXY) ALKYLAMIDES AND THEIR USE AS FUNGICIDES | SYNGENTA LIMITED (GB) | 2004-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194763-A1 | N-alkynyl-2-(substituted phenoxy) alkylamides and their use as fungicides | CYP4X1, PRXL2A, CYP1A2 | ALDH1A1 1112/4885HPGD 4709/4885L3MBTL1 500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.