Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAT | P00750 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL459381 | 0.76 | SLC6A4 (0.41) | — | |
| SCHEMBL461249 | 0.69 | PIM1 (0.31) | PLATCNR2 | |
| SCHEMBL461088 | 0.68 | PLAT (0.31) | PLAT | |
| SCHEMBL461993 | 0.62 | SLC6A4 (0.37) | MAOAMAOBKDM1A | |
| SCHEMBL460168 | 0.61 | SLC6A4 (0.46) | — | |
| SCHEMBL470452 | 0.61 | GPR119 (0.51) | — | |
| SCHEMBL13186592 | 0.61 | GPR119 (0.39) | PLAT | |
| SCHEMBL458445 | 0.61 | GPR119 (0.54) | — | |
| SCHEMBL458214 | 0.61 | PLAT (0.34) | PLATMAOAMAOB | |
| SCHEMBL1673933 | 0.61 | NR1H4 (0.47) | PLATCNR2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |