Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 9/20 | 0.45 |
| ▸ | GGPS1 | O95749 | 5/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27963402 | 1.00 | FDPS (0.45) | FDPSGGPS1SMPD1CES2ALDH1A1 | |
| SCHEMBL16755474 | 0.82 | CES2 (0.47) | FDPSGGPS1SMPD1CES2 | |
| SCHEMBL8466412 | 0.80 | SMPD1 (0.45) | FDPSSMPD1CES2ALDH1A1TSHR | |
| SCHEMBL7619946 | 0.80 | SMPD1 (0.45) | FDPSSMPD1CES2ALDH1A1TSHR | |
| SCHEMBL8464966 | 0.80 | SMPD1 (0.45) | FDPSSMPD1CES2ALDH1A1TSHR | |
| SCHEMBL8422908 | 0.80 | SMPD1 (0.45) | FDPSSMPD1CES2ALDH1A1TSHR | |
| SCHEMBL3284980 | 0.80 | SMPD1 (0.45) | FDPSSMPD1CES2ALDH1A1TSHR | |
| SCHEMBL8772566 | 0.80 | FDPS (0.50) | FDPSGGPS1SMPD1CES2 | |
| SCHEMBL6002240 | 0.80 | SMPD1 (0.45) | FDPSSMPD1CES2ALDH1A1TSHR | |
| SCHEMBL658156 | 0.80 | SMPD1 (0.45) | FDPSSMPD1CES2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773765-B1 | METHOD FOR CATALYTIC HYDROGENATION PURIFICATION OF LACTAM CONTAINING CHOROLACTAM IMPURITIES | ARKEMA FRANCE (FR) | 2008-04-23 | — | — | EP | disclosed |
| EP-1773765-A2 | METHOD FOR CATALYTIC HYDROGENATION PURIFICATION OF LACTAM CONTAINING CHOROLACTAM IMPURITIES | Arkema France (FR) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006016060-A2 | METHOD FOR CATALYTIC HYDROGENATION PURIFICATION OF LACTAM CONTAINING CHOROLACTAM IMPURITIES | ARKEMA FRANCE (FR) | 2006-02-16 | — | — | WO | disclosed |