Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4804512 | 0.76 | ESR1 (0.46) | CA2ALDH1A1TDP1KDM4E | |
| SCHEMBL3675112 | 0.76 | DAO (0.41) | IDO1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL94148 | 0.75 | MAOA (0.48) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8094050 | 0.74 | POLB (0.76) | POLBLOXL2TSHRCA12CA1 | |
| SCHEMBL8087428 | 0.74 | POLB (0.76) | POLBLOXL2TSHRCA12CA1 | |
| SCHEMBL44366 | 0.74 | POLB (0.76) | POLBLOXL2TSHRCA12CA1 | |
| SCHEMBL18973131 | 0.72 | HAO1 (0.38) | CA12CA2CA9MEN1KMT2A | |
| SCHEMBL18973135 | 0.72 | MAPT (0.40) | POLBALDH1A1MAPTLMNA | |
| SCHEMBL9348586 | 0.71 | CYP3A4 (0.43) | POLBCA12CA1CA2CA9 | |
| SCHEMBL3684146 | 0.70 | SRD5A2 (0.47) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351982-B1 | X RAY CRYSTAL STRUCTURES AT 5.5 A RESOLUTION OF FUNCTIONAL COMPLEXES OF THE BACTERIAL RIBOSOME CONTAINING TRANSFER RNA AND MODEL MESSENGER RNAS | UNIV CALIFORNIA (US) | 2008-02-13 | — | — | EP | disclosed |
| US-7133783-B2 | X-ray crystal structures of functional ribosome complexes containing transfer RNA and model messenger RNAs and methods of use | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-11-07 | — | — | US | disclosed |
| US-20020188108-A1 | X-ray crystal structures of functional ribosome complexes containing transfer RNA and model messenger RNAs and methods of use | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-12-12 | — | — | US | disclosed |