Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CASP2 | P42575 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9717465 | 0.79 | MEN1 (0.48) | HTTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL15059988 | 0.77 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1SMN1; SMN2NAAA | |
| SCHEMBL10309103 | 0.77 | HDAC6 (0.42) | MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9717412 | 0.77 | NAAA (0.56) | MEN1KMT2AALDH1A1SMN1; SMN2NAAA | |
| SCHEMBL3429965 | 0.77 | — | — | |
| SCHEMBL620134 | 0.75 | NAAA (0.54) | MEN1KMT2AALDH1A1SMN1; SMN2NAAA | |
| SCHEMBL6433502 | 0.75 | — | — | |
| SCHEMBL6940499 | 0.75 | NAAA (0.54) | MEN1KMT2AALDH1A1SMN1; SMN2NAAA | |
| SCHEMBL9717404 | 0.75 | TSHR (0.56) | MEN1KMT2AALDH1A1SMN1; SMN2NAAA | |
| SCHEMBL12834799 | 0.75 | NAAA (0.65) | MEN1KMT2AALDH1A1SMN1; SMN2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008081348-A2 | METHOD AND COMPOSITION FOR PERMANENTLY SHAPING HAIR | THE PROCTER & GAMBLE COMPANY (US) | 2008-07-10 | — | — | WO | claimed |
| US-20080075682-A1 | Method and composition for permanently shaping hair | THE PROCTER & GAMBLE COMPANY | 2008-03-27 | — | — | US | claimed |
| US-20080075681-A1 | Method and composition for permanently shaping hair | PROCTER & GAMBLE COMPANY, THE | 2008-03-27 | — | — | US | claimed |
| WO-2008012733-A2 | METHOD AND COMPOSITION FOR PERMANENTLY SHAPING HAIR | THE PROCTER & GAMBLE COMPANY (US) | 2008-01-31 | — | — | WO | claimed |
| WO-2008012732-A2 | METHOD AND COMPOSITION FOR PERMANENTLY SHAPING HAIR | THE PROCTER & GAMBLE COMPANY (US) | 2008-01-31 | — | — | WO | claimed |
| US-20080025937-A1 | Method and composition for permanently shaping hair | PROCTER & GAMBLE COMPANY, THE | 2008-01-31 | — | — | US | claimed |
| US-20080025938-A1 | Method and composition for permanently shaping hair | PROCTER & GAMBLE COMPANY, THE | 2008-01-31 | — | — | US | claimed |
| US-20080025939-A1 | Method and composition for permanently shaping hair | PROCTER & GAMBLE COMPANY, THE | 2008-01-31 | — | — | US | claimed |
| WO-2008012730-A2 | METHOD AND COMPOSITION FOR PERMANENTLY SHAPING HAIR | THE PROCTER & GAMBLE COMPANY (US) | 2008-01-31 | — | — | WO | claimed |
| EP-1880710-A1 | Method and composition for permanently shaping hair | Wella Aktiengesellschaft (DE) | 2008-01-23 | — | — | EP | claimed |
| EP-1880709-A1 | Method and composition for permanently shaping hair | Wella Aktiengesellschaft (DE) | 2008-01-23 | — | — | EP | claimed |
| EP-1880706-A1 | Method and composition for permanently shaping hair | Wella Aktiengesellschaft (DE) | 2008-01-23 | — | — | EP | claimed |
| EP-1880707-A1 | Method and composition for permanently shaping hair | Wella Aktiengesellschaft (DE) | 2008-01-23 | — | — | EP | claimed |
| EP-1880708-A1 | Method and composition for permanently shaping hair | Wella Aktiengesellschaft (DE) | 2008-01-23 | — | — | EP | claimed |
| US-20230329991-A1 | PERMANENT HAIR SHAPING COMPOSITION | WELLA GERMANY GMBH (DE) | 2023-10-19 | — | — | US | disclosed |
| US-11779530-B2 | Composition for the permanent deformation of hair having reduced odor | WELLA OPERATIONS US, LLC (US) | 2023-10-10 | — | — | US | disclosed |
| EP-4216912-A1 | PERMANENT HAIR SHAPING COMPOSITION | Wella Germany GmbH (DE) | 2023-08-02 | — | — | EP | disclosed |
| EP-1880709-A1 | Method and composition for permanently shaping hair | Wella Aktiengesellschaft (DE) | 2008-01-23 | — | — | EP | disclosed |
| EP-1880706-A1 | Method and composition for permanently shaping hair | Wella Aktiengesellschaft (DE) | 2008-01-23 | — | — | EP | disclosed |
| EP-1880708-A1 | Method and composition for permanently shaping hair | Wella Aktiengesellschaft (DE) | 2008-01-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080025937-A1 | Method and composition for permanently shaping hair | DNMT3A, DNMT1, NACA | HTT 747/4885MEN1 3081/4885KMT2A 439/4885 |
| US-20080025938-A1 | Method and composition for permanently shaping hair | KRT18, HHAT, AADAT | HTT 636/4885MEN1 4282/4885KMT2A 183/4885 |
| US-11779530-B2 | Composition for the permanent deformation of hair having reduced odor | OR51E2, MAL2, OR10J3 | HTT 2120/4885MEN1 2717/4885KMT2A 2931/4885 |
| US-20080075682-A1 | Method and composition for permanently shaping hair | DNMT1, DNMT3A, KRT18 | HTT 879/4885MEN1 3225/4885KMT2A 95/4885 |
| US-20080075681-A1 | Method and composition for permanently shaping hair | AQP3, SLC3A2, SLC27A2 | HTT 989/4885MEN1 3001/4885KMT2A 351/4885 |
| US-20080025939-A1 | Method and composition for permanently shaping hair | DNMT3A, DNMT1, TET2 | HTT 1283/4885MEN1 2797/4885KMT2A 314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.