Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.60 |
| ▸ | GAA | P10253 | 8/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | THRB | P10828 | 3/20 | 0.60 |
| ▸ | RECQL | P46063 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1052285 | 0.81 | ALDH1A1 (0.46) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL28685254 | 0.81 | NR4A1 (0.56) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL31286071 | 0.80 | ALDH1A1 (0.55) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL1024889 | 0.80 | ALDH1A1 (0.55) | ALDH1A1GAAMAPTMEN1KMT2A | |
| Boric Acid SCHEMBL28096470 | 0.79 | ALDH1A1 (0.50) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL7887616 | 0.78 | ESR1 (0.52) | ALDH1A1MAPTKDM4ETDP1PKM | |
| SCHEMBL31376356 | 0.78 | TMEM97 (0.40) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL20215002 | 0.78 | ALDH1A1 (0.46) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL30623356 | 0.77 | ALDH1A1 (0.52) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL6938751 | 0.77 | ALDH1A1 (0.52) | ALDH1A1GAAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100593541-C | Benzopyran derivatives substituted with a thioxobenzoxazole derivative, their pharmaceutically acceptable salts, their preparation and pharmaceutical compositions containing them | DONGBU HANNONG CHEMICAL CO LTD | 2010-03-10 | — | — | CN | disclosed |
| US-7420060-B2 | Benzopyran derivatives substituted with a thioxobenzoxazole derivative, pharmaceutically acceptable salts thereof, their preparations and pharmaceutical compositions containing them | SCHAEFFLER KG (DE) | 2008-09-02 | — | — | US | disclosed |
| EP-1626968-A4 | BENZOPYRAN DERIVATIVES SUBSTITUTED WITH A THIOXOBENZOXAZOLE DERIVATIVE, PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, THEIR PREPARATIONS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DONGBU HANNONG CHEMICAL CO LTD (KR) | 2008-03-05 | — | — | EP | disclosed |
| US-20070093481-A1 | Benzopyran derivatives substituted with a thioxobenzoxazole derivative, pharmaceutically acceptable salts thereof, their preparations and pharmaceutical compositions containingthem | DONGBU HANNONG CHEMICAL CO., LTD. (KR) | 2007-04-26 | — | — | US | disclosed |
| CN-1795192-A | Benzopyran derivatives substituted with a thioxobenzoxazole derivative, pharmaceutically acceptable salts thereof, their preparations and pharmaceutical compositions containing them | DONGBU HANNONG CHEMICAL CO LTD (KR) | 2006-06-28 | — | — | CN | disclosed |
| EP-1626968-A1 | BENZOPYRAN DERIVATIVES SUBSTITUTED WITH A THIOXOBENZOXAZOLE DERIVATIVE, PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, THEIR PREPARATIONS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dongbu Hannong Chemical Co., Ltd. (KR) | 2006-02-22 | — | — | EP | disclosed |
| WO-2004106331-A1 | BENZOPYRAN DERIVATIVES SUBSTITUTED WITH A THIOXOBENZOXAZOLE DERIVATIVE, PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, THEIR PREPARATIONS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DONGBU HANNONG CHEMICAL CO., LTD (KR) | 2004-12-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070093481-A1 | Benzopyran derivatives substituted with a thioxobenzoxazole derivative, pharmaceutically acceptable salts thereof, their preparations and pharmaceutical compositions containingthem | TNNT2, TNNI3, BRIX1 | ALDH1A1 436/4885GAA 1748/4885MAPT 1409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.