Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | VDR | P11473 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4617403 | 1.00 | PKM (0.41) | PKMKCNA5KMT2AMEN1CYP2D6 | |
| SCHEMBL9475352 | 0.85 | VDR (0.46) | CYP2D6MAPK1CA12CYP1A2CYP3A4 | |
| SCHEMBL7305249 | 0.80 | ALDH1A1 (0.42) | PKMKCNA5CYP2D6MAPK1CA12 | |
| SCHEMBL13105251 | 0.79 | ALDH1A1 (0.40) | KMT2AMEN1CA12CYP3A4CA9 | |
| SCHEMBL16377449 | 0.79 | VDR (0.47) | PKMKMT2AMEN1CYP2D6MAPK1 | |
| SCHEMBL4618425 | 0.79 | HTT (0.37) | PKMKCNA5KMT2AMEN1CYP2D6 | |
| SCHEMBL5468129 | 0.79 | GAA (0.42) | KMT2AMEN1CA12CYP3A4CA9 | |
| SCHEMBL5468126 | 0.79 | GAA (0.42) | KMT2AMEN1CA12CYP3A4CA9 | |
| SCHEMBL6005429 | 0.78 | RECQL (0.40) | PKMKMT2AMEN1CYP2D6MAPK1 | |
| SCHEMBL10970992 | 0.77 | MAPK1 (0.43) | PKMKMT2AMEN1CYP2D6MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891005-A2 | PROCESS FOR PREPARATION OF 13,14-DIHYDRO-PGF2 ALPHA DERIVATIVES | INSTYTUT FARMACEUTYCZNY (PL) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006112742-A2 | PROCESS FOR PREPARATION OF 13,14-DIHYDRO-PGF2α DERIVATIVES | INSTYTUT FARMACEUTYCZNY (PL) | 2006-10-26 | — | — | WO | disclosed |