Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | VDR | P11473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16377449 | 0.84 | VDR (0.47) | MAPK1CYP2D6PKMVDRHTT | |
| SCHEMBL9475352 | 0.80 | VDR (0.46) | MAPK1CYP2D6VDRHTTSMN1; SMN2 | |
| SCHEMBL6762680 | 0.80 | VDR (0.46) | MAPK1CYP2D6VDRHTTSMN1; SMN2 | |
| SCHEMBL491994 | 0.79 | VDR (0.45) | MAPK1CYP2D6VDRHTTSMN1; SMN2 | |
| SCHEMBL11988007 | 0.79 | VDR (0.45) | MAPK1CYP2D6VDRHTTSMN1; SMN2 | |
| SCHEMBL6337405 | 0.78 | MAPK1 (0.46) | MAPK1CYP2D6PKMVDRHTT | |
| SCHEMBL11260413 | 0.78 | KEAP1 (0.46) | MAPK1CYP2D6PKMVDRHTT | |
| SCHEMBL30190441 | 0.78 | PKM (0.45) | MAPK1CYP2D6PKMVDRHTT | |
| SCHEMBL17164172 | 0.77 | GSR (0.46) | MAPK1CYP2D6PKMVDRHTT | |
| SCHEMBL6982213 | 0.77 | GSR (0.46) | MAPK1CYP2D6PKMVDRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0132225-A2 | Curing of acid-curable compositions containing a blocked catalyst with the aid of heat | CIBA-GEIGY AG (CH) | 1985-01-23 | — | — | EP | disclosed |