SCHEMBL461671

SCHEMBL461671

C=CC1(Cc2ccccc2)CCC1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAOA P21397 6/20 0.45
MAOB P27338 6/20 0.45
LMNA P02545 1/20 0.36
HTT P42858 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
OPRL1 P41146 3/20 0.35
OPRM1 P35372 2/20 0.35
OPRK1 P41145 2/20 0.35
SIGMAR1 Q99720 1/20 0.34
KDM1A O60341 3/20 0.34
CYP3A4 P08684 1/20 0.34
HSD17B10 Q99714 1/20 0.34
OPRD1 P41143 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28528939 0.76 MAOA (0.45) MAOAMAOBLMNAHTTNPSR1
SCHEMBL3619222 0.74 MAOA (0.44) MAOAMAOBLMNAHTTNPSR1
SCHEMBL6672637 0.72 MAOA (0.50) MAOAMAOBLMNAHTTNPSR1
SCHEMBL6672640 0.72 MAOA (0.50) MAOAMAOBOPRL1OPRM1OPRK1
SCHEMBL156160 0.72 MAOA (0.54) MAOAMAOBOPRL1OPRM1OPRK1
SCHEMBL4642677 0.71 MAOB (0.48) MAOAMAOBLMNAHTTNPSR1
SCHEMBL9442104 0.71 MAOB (0.48) MAOAMAOBLMNAHTTNPSR1
SCHEMBL24271102 0.71 CARM1 (0.41) MAOAMAOBLMNAOPRL1OPRM1
SCHEMBL28436093 0.71 MAOA (0.40) MAOAMAOBLMNAHTTNPSR1
SCHEMBL24114951 0.70 ALDH1A1 (0.31) HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 262 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0765888-B1 Psuedo-random polymers of an alpha-olefin and a polymerizable vinylidene monomer DOW GLOBAL TECHNOLOGIES INC (US) 2007-08-29 EP claimed
US-12552880-B2 Advanced quality control tools for manufacturing bimodal and multimodal polyethylene resins CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2026-02-17 US disclosed
EP-4646448-A1 DIRECT ETHYLENE INJECTION FOR DUAL REACTOR SOLUTION PROCESS Dow Global Technologies LLC (US) 2025-11-12 EP disclosed
WO-2025226645-A1 BIMODAL ETHYLENE-BASED POLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2025-10-30 WO disclosed
WO-2025226646-A1 BIMODAL ETHYLENE-BASED POLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2025-10-30 WO disclosed
WO-2024147973-A1 DIRECT ETHYLENE INJECTION FOR DUAL REACTOR SOLUTION PROCESS DOW GLOBAL TECHNOLOGIES LLC (US) 2024-07-11 WO disclosed
EP-3887413-B1 IMPROVED MELT FLOW INDEX RESPONSE IN POLYETHYLENE REACTORS CHEVRON PHILLIPS CHEMICAL CO LP (US) 2024-06-12 EP disclosed
US-11969725-B2 Reactor jacket design CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2024-04-30 US disclosed
US-11802865-B2 Utilizing aTREF data with chemometric analysis for determining the types of polyethylene present in polymer blends and multilayer films CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2023-10-31 US disclosed
US-20230322973-A1 Advanced Quality Control Tools for Manufacturing Bimodal and Multimodal Polyethylene Resins CHEVRON PHILLIPS CHEMICAL COMPANY LP 2023-10-12 US disclosed
US-5582923-A Extrusion compositions having high drawdown and substantially reduced neck-in THE DOW CHEMICAL COMPANY (US) 1996-12-10 US disclosed
WO-1996035750-A1 MEDIUM MODULUS MOLDED MATERIAL COMPRISING SUBSTANTIALLY LINEAR POLYETHYLENE AND FABRICATION METHOD THE DOW CHEMICAL COMPANY (US) 1996-11-14 WO disclosed
WO-1996016119-A1 EXTRUSION COMPOSITIONS HAVING HIGH DRAWDOWN AND SUBSTANTIALLY REDUCED NECK-IN THE DOW CHEMICAL COMPANY (US) 1996-05-30 WO disclosed
WO-1996012762-A1 POLYOLEFIN COMPOSITIONS EXHIBITING HEAT RESISTIVITY, LOW HEXANE-EXTRACTIVES AND CONTROLLED MODULUS THE DOW CHEMICAL COMPANY (US) 1996-05-02 WO disclosed
US-5504223-A Synthesis of cyclopentadienyl metal coordination complexes from metal hydrocarbyloxides THE DOW CHEMICAL COMPANY (US) 1996-04-02 US disclosed
EP-0689562-A4 PROCESS FOR MAKING ETHYLENIC POLYMER FOAM STRUCTURES DOW CHEMICAL CO (US) 1996-03-13 EP disclosed
WO-1996000734-A1 GROUP 4 METAL DIENE COMPLEXES AND ADDITION POLYMERIZATION CATALYSTS THEREFROM THE DOW CHEMICAL COMPANY (US) 1996-01-11 WO disclosed
EP-0689562-A1 PROCESS FOR MAKING ETHYLENIC POLYMER FOAM STRUCTURES THE DOW CHEMICAL COMPANY (US) 1996-01-03 EP disclosed
WO-1994021717-A1 PROCESS FOR MAKING ETHYLENIC POLYMER FOAM STRUCTURES THE DOW CHEMICAL COMPANY (US) 1994-09-29 WO disclosed
EP-0416815-A2 Constrained geometry addition polymerization catalysts, processes for their preparation, precursors therefor, methods of use, and novel polymers formed therewith THE DOW CHEMICAL COMPANY (US) 1991-03-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552880-B2 Advanced quality control tools for manufacturing bimodal and multimodal polyethylene resins RAB5IF, RPS28, RPL28 MAOA 4841/4885MAOB 4862/4885LMNA 2265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.