SCHEMBL4642677

SCHEMBL4642677

O=CC1(Cc2ccccc2)CC1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAOB P27338 8/20 0.48
MAOA P21397 7/20 0.48
LMNA P02545 1/20 0.42
HTT P42858 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ADH1B P00325 1/20 0.39
ADH1C P00326 1/20 0.39
ADH1A P07327 1/20 0.39
ADH7 P40394 1/20 0.39
OPRL1 P41146 3/20 0.37
OPRM1 P35372 2/20 0.37
OPRK1 P41145 2/20 0.37
KDM1A O60341 4/20 0.36
EPHX1 P07099 1/20 0.35
ELANE P08246 1/20 0.35
HSD11B1 P28845 1/20 0.35
OPRD1 P41143 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28528939 0.92 MAOA (0.45) MAOBMAOALMNAHTTNPSR1
SCHEMBL3619222 0.90 MAOA (0.44) MAOBMAOALMNAHTTNPSR1
SCHEMBL8305284 0.87 TSHR (0.42) MAOBMAOALMNAHTTNPSR1
SCHEMBL1668138 0.86 L3MBTL1 (0.41) MAOBMAOALMNAHTTNPSR1
SCHEMBL3160388 0.79 IDO1 (0.37) LMNAHSD11B1
SCHEMBL9442104 0.78 MAOB (0.48) MAOBMAOALMNAHTTNPSR1
SCHEMBL6170590 0.75 TSHR (0.48) MAOBMAOA
SCHEMBL3155533 0.72 ALDH1A1 (0.40) HSD11B1
SCHEMBL22798189 0.71 MAOA (0.50) MAOBMAOALMNAHTTNPSR1
SCHEMBL461671 0.71 MAOA (0.45) MAOBMAOALMNAHTTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1298490-B1 Photopolymerizable composition and recording material FUJIFILM CORP (JP) 2008-08-13 EP disclosed
US-7118844-B2 Diazonium salt and thermal recording material using the same FUJI PHOTO FILM CO., LTD. (JP) 2006-10-10 US disclosed
US-20060205594-A1 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. 2006-09-14 US disclosed
EP-1253466-B1 Diazonium salt and heat-sensitive recording material FUJI PHOTO FILM CO LTD (JP) 2006-05-31 EP disclosed
US-20060089357-A1 Novel compounds and compositions as cathepsin inhibitors AVENTIS PHARMACEUTICALS INC. (US) 2006-04-27 US disclosed
US-7030116-B2 Compounds and compositions as cathepsin inhibitors AVENTIS PHARMACEUTICALS INC. (US) 2006-04-18 US disclosed
US-20050272604-A1 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. 2005-12-08 US disclosed
US-20050260518-A1 Heat sensitive recording material and microcapsule FUJI PHOTO FILM CO., LTD. 2005-11-24 US disclosed
EP-1598208-A2 Heat-sensitive recording material Fuji Photo Film Co., Ltd. (JP) 2005-11-23 EP disclosed
EP-1598206-A2 Heat sensitive recording material and microcapsule FUJI PHOTO FILM CO., LTD. (JP) 2005-11-23 EP disclosed
EP-1253466-A1 Diazonium salt and heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 2002-10-30 EP disclosed
US-20020091065-A1 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. 2002-07-11 US disclosed
US-20020086797-A1 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. 2002-07-04 US disclosed
US-6348433-B1 3-PHENYLSULFONYL-3,4-DIHYDROBENZO(E)TRIAZIN-4-ONE DERIVATIVES; STORAGE STABILITY; HIGH DENSITY COLOR DEVELOPMENT; RADIATION RESISTANCE FUJI PHOTO FILM CO., LTD. (JP) 2002-02-19 US disclosed
EP-0827020-B1 Thermal recording material FUJI PHOTO FILM CO LTD (JP) 2001-12-05 EP disclosed
US-6248497-B1 LIGHT SENSITIVE AND HEAT SENSITIVE RECORDING IMAGES FUJI PHOTO FILM CO., LTD. (JP) 2001-06-19 US disclosed
US-6245476-B1 SUPPORTS WITH DIAZO COMPOUNDS IN MICROCAPSULES FUJI PHOTO FILM CO., LTD. (JP) 2001-06-12 US disclosed
US-6017672-A MIXTURE OF DIAZONIUM SALT HAVING ABSORPTION WAVELENGTH SHORTER THAN 350 NANOMETERS AND A THERMALLY REACTIVE COUPLER CONTAINED WITHIN RECORDING LAYER COATED ONTO SUPPORT; STORAGE STABILITY, PHOTOSTABILITY, HIGH COLOR DENSITY FUJI PHOTO FILM CO., LTD. (JP) 2000-01-25 US disclosed
US-5998082-A DIHYDROCARBYLOXYPHENYL DIAZONIUM COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1999-12-07 US disclosed
EP-0827020-A1 Thermal recording material FUJI PHOTO FILM CO., LTD. (JP) 1998-03-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060089357-A1 Novel compounds and compositions as cathepsin inhibitors CTSS, CTSB, CTSE MAOB 336/4885MAOA 501/4885LMNA 1701/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.