Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL899648 | 0.81 | ALDH1A1 (0.50) | ALDH1A1GAASMN1; SMN2TDP1MEN1 | |
| SCHEMBL899647 | 0.81 | ALDH1A1 (0.50) | ALDH1A1GAASMN1; SMN2TDP1MEN1 | |
| SCHEMBL28026694 | 0.80 | TDP1 (0.49) | ALDH1A1GAASMN1; SMN2TDP1MEN1 | |
| SCHEMBL8398671 | 0.80 | TDP1 (0.49) | ALDH1A1GAASMN1; SMN2TDP1MEN1 | |
| SCHEMBL27556368 | 0.80 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1GAASMN1; SMN2TDP1 | |
| SCHEMBL5153725 | 0.78 | GPR35 (0.51) | ALDH1A1L3MBTL1GAASMN1; SMN2MEN1 | |
| SCHEMBL4231830 | 0.77 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1GAASMN1; SMN2TDP1 | |
| SCHEMBL14032363 | 0.77 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL9644637 | 0.77 | ALDH1A1 (0.50) | ALDH1A1GAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4236872 | 0.76 | CYP1A2 (0.66) | ALDH1A1L3MBTL1GAASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8674121-B2 | Process for the production of benzofurans | SANOFI (FR) | 2014-03-18 | — | — | US | claimed |
| EP-2435398-B1 | PROCESS FOR THE PRODUCTION OF BENZOFURANS | SANOFI SA (FR) | 2014-01-22 | — | — | EP | claimed |
| US-20120065411-A1 | PROCESS FOR THE PRODUCTION OF BENZOFURANS | SANOFI (FR) | 2012-03-15 | — | — | US | claimed |
| US-8674121-B2 | Process for the production of benzofurans | SANOFI (FR) | 2014-03-18 | — | — | US | disclosed |
| US-8674121-B2 | Process for the production of benzofurans | SANOFI (FR) | 2014-03-18 | — | — | US | disclosed |
| EP-2435398-B1 | PROCESS FOR THE PRODUCTION OF BENZOFURANS | SANOFI SA (FR) | 2014-01-22 | — | — | EP | disclosed |
| CN-102459146-A | Process for preparing benzofurans | SANOFI SA | 2012-05-16 | — | — | CN | disclosed |
| EP-2435398-A1 | PROCESS FOR THE PRODUCTION OF BENZOFURANS | SANOFI (FR) | 2012-04-04 | — | — | EP | disclosed |
| US-20120065411-A1 | PROCESS FOR THE PRODUCTION OF BENZOFURANS | SANOFI (FR) | 2012-03-15 | — | — | US | disclosed |
| US-20120065411-A1 | PROCESS FOR THE PRODUCTION OF BENZOFURANS | SANOFI (FR) | 2012-03-15 | — | — | US | disclosed |
| WO-2010136500-A1 | PROCESS FOR THE PRODUCTION OF BENZOFURANS | SANOFI-AVENTIS (FR) | 2010-12-02 | — | — | WO | disclosed |
| WO-2010136500-A1 | PROCESS FOR THE PRODUCTION OF BENZOFURANS | SANOFI-AVENTIS (FR) | 2010-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065411-A1 | PROCESS FOR THE PRODUCTION OF BENZOFURANS | CYP2F1, CYP2B6, CYP4F2 | ALDH1A1 335/4885L3MBTL1 3348/4885GAA 255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.