Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9584860 | 0.87 | KDM4E (0.46) | ALDH1A1L3MBTL1MAPTNPSR1GLA | |
| 1,2-Diethoxybenzene SCHEMBL578986 | 0.87 | ALDH1A1 (0.68) | ALDH1A1L3MBTL1MAPTNPSR1GLA | |
| 1,2-Diethoxybenzene SCHEMBL29428929 | 0.87 | ALDH1A1 (0.68) | ALDH1A1L3MBTL1MAPTNPSR1GLA | |
| SCHEMBL7330758 | 0.82 | L3MBTL1 (0.60) | ALDH1A1L3MBTL1MAPTNPSR1GLA | |
| SCHEMBL9209498 | 0.82 | CYP1A2 (0.47) | ALDH1A1L3MBTL1MAPTNPSR1TDP1 | |
| SCHEMBL402370 | 0.81 | CA1 (0.62) | ALDH1A1L3MBTL1TDP1CYP1A2LMNA | |
| SCHEMBL10997495 | 0.81 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1MAPTNPSR1GLA | |
| SCHEMBL11152823 | 0.80 | L3MBTL1 (0.61) | ALDH1A1L3MBTL1MAPTNPSR1GLA | |
| SCHEMBL6536519 | 0.80 | CYP1A2 (0.60) | L3MBTL1MAPTNPSR1TDP1CYP1A2 | |
| 1,2-Diethoxybenzene SCHEMBL8912901 | 0.80 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1MAPTNPSR1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080033207-A1 | Preparation of R-5- (2-(2-Ethoxyphenoxyetylamino) -2-Methoxybenzen-Sulphonamide Hydrochloride of High Chemical | LEK PHARMACEUTICALS D.D. (SI) | 2008-02-07 | — | — | US | claimed |
| JP-2007517797-A | — | — | 2007-07-05 | — | — | JP | claimed |
| CN-1902166-A | Preparation of r-5-(2-(2-ethoxyphenoxyethylamino)propyl)-2-methoxybenzenesulphonamide hydrochloride of high chemical purity | LEK PHARMACEUTICALS (SI) | 2007-01-24 | — | — | CN | claimed |
| EP-1708990-A1 | PREPARATION OF R-5-(2-(2-ETHOXYPHENOXYETHYLAMINO)PROPYL)-2-METHOXYBENZENESULPHONAMIDE HYDROCHLORIDE OF HIGH CHEMICAL PURITY | LEK Pharmaceuticals D.D. (SI) | 2006-10-11 | — | — | EP | claimed |
| WO-2005063702-A1 | PREPARATION OF R-5-(2-(2-ETHOXYPHENOXYETYLAMINO)PROPYL)-2- METHOXYBENZENESULPHONAMIDE HYDROCHLORIDE OF HIGH CHEMICAL | LEK PHARMACEUTICALS D.D. (CH) | 2005-07-14 | — | — | WO | claimed |
| EP-0822814-A4 | ALPHA 1a ADRENERGIC RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 1998-12-09 | — | — | EP | claimed |
| EP-0822814-A1 | ALPHA 1a ADRENERGIC RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1998-02-11 | — | — | EP | claimed |
| WO-1996032938-A1 | ALPHA 1a ADRENERGIC RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1996-10-24 | — | — | WO | claimed |
| CN-115232034-B | Synthesis method of tamsulosin hydrochloride | 上药康丽（常州）药业有限公司 | 2024-02-20 | — | — | CN | disclosed |
| WO-2022149081-A1 | IMPROVED PROCESS FOR THE PREPARATION OF A COMPOUND USEFUL IN THE PREPARATION OF ANTI-ANDROGENIC COMPOUND | OCIMUM LABS PRIVATE LIMITED (IN) | 2022-07-14 | — | — | WO | disclosed |
| CN-103664538-A | Method for preparing 2-(2-ethoxyphenoxy) ethyl bromide | CHINA MEDICINE RES & DEV CT CO LTD | 2014-03-26 | — | — | CN | disclosed |
| CN-100584826-C | Preparation of r-5-(2-(2-ethoxyphenoxyethylamino)propyl)-2-methoxybenzenesulphonamide hydrochloride of high chemical purity | LEK PHARMACEUTICALS | 2010-01-27 | — | — | CN | disclosed |
| EP-1885692-A2 | PROCESS FOR THE PREPARATION OF TAMSULOSIN | Medichem, S.A. (ES) | 2008-02-13 | — | — | EP | disclosed |
| US-20080033207-A1 | Preparation of R-5- (2-(2-Ethoxyphenoxyetylamino) -2-Methoxybenzen-Sulphonamide Hydrochloride of High Chemical | LEK PHARMACEUTICALS D.D. (SI) | 2008-02-07 | — | — | US | disclosed |
| EP-0822814-A1 | ALPHA 1a ADRENERGIC RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1998-02-11 | — | — | EP | disclosed |
| US-5668148-A | BENIGN PROSTATIC HYPERTROPHY | MERCK & CO., INC. (US) | 1997-09-16 | — | — | US | disclosed |
| WO-1996032938-A1 | ALPHA 1a ADRENERGIC RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1996-10-24 | — | — | WO | disclosed |
| EP-0054132-B1 | PYRIMIDONES, THEIR PREPARATION AND MEDICINES CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1984-10-10 | — | — | EP | disclosed |
| US-4379788-A | HYPOTENSIVES, ANTIARRHYTHMIA, B-BLOCKERS | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-04-12 | — | — | US | disclosed |
| EP-0054132-A1 | Pyrimidones, their preparation and medicines containing them | Dr. Karl Thomae GmbH (DE) | 1982-06-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080033207-A1 | Preparation of R-5- (2-(2-Ethoxyphenoxyetylamino) -2-Methoxybenzen-Sulphonamide Hydrochloride of High Chemical | ADRA2C, ADRB2, REN | ALDH1A1 2115/4885L3MBTL1 4842/4885MAPT 3021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.