⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18824669 | 0.75 | PIK3CA (0.38) | — | |
| SCHEMBL18614347 | 0.75 | LMNA (0.40) | — | |
| SCHEMBL31507012 | 0.75 | CHRM4 (0.42) | — | |
| SCHEMBL31489904 | 0.75 | CYP1A2 (0.39) | — | |
| SCHEMBL21604521 | 0.72 | CHRNB2 (0.33) | — | |
| SCHEMBL24330410 | 0.71 | TDP1 (0.44) | — | |
| SCHEMBL31391471 | 0.71 | TRPV4 (0.42) | — | |
| SCHEMBL25344221 | 0.69 | RAB9A (0.40) | — | |
| SCHEMBL18614417 | 0.66 | SCD (0.35) | — | |
| SCHEMBL1822085 | 0.65 | XDH (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260092073-A1 | NOVEL COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2026-04-02 | — | — | US | disclosed |
| WO-2024218100-A1 | OXAZOLO[4,5-B]PYRAZINE AND OXAZOLO[4,5-B]PYRIDINE DERIVATIVES AS NLRP3 INHIBITORS FOR THE TREATMENT OF E.G. INFLAMMATORY DISEASES | F. HOFFMANN-LA ROCHE AG (CH) | 2024-10-24 | — | — | WO | disclosed |
| CN-116731038-A | Nitrogen-containing heterocyclic compound, and preparation method and application thereof | 苏州亚盛药业有限公司 | 2023-09-12 | — | — | CN | disclosed |
| EP-3632918-A1 | LIGAND COMPOUND OF 7 NICOTINIC ACETYLCHOLINE RECEPTOR AND APPLICATION THEREOF | Beijing Normal University (CN) | 2020-04-08 | — | — | EP | disclosed |
| US-20080124732-A1 | METHOD FOR OPTICAL MEASUREMENT OF MULTI-STRANDED NUCLEIC ACID | FUJIFILM CORPORATION | 2008-05-29 | — | — | US | disclosed |
| EP-1889880-A2 | Method for optical measurement of multi-stranded nucleic acid | FUJIFILM Corporation (JP) | 2008-02-20 | — | — | EP | disclosed |
| EP-1362894-B1 | Method for optical measurement of multi-stranded nucleic acid using cyanine dyes | FUJIFILM CORP (JP) | 2007-12-19 | — | — | EP | disclosed |
| US-20050112770-A1 | Method for optical measurement of multi-stranded nucleic acid | FUJI PHOTO FILM CO., LTD. | 2005-05-26 | — | — | US | disclosed |
| EP-1362894-A2 | Method for optical measurement of multi-stranded nucleic acid using cyanine dyes | FUJI PHOTO FILM CO., LTD. (JP) | 2003-11-19 | — | — | EP | disclosed |