Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKLR | P30613 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 5/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 4/20 | 0.40 |
| ▸ | MMP3 | P08254 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4619146 | 1.00 | PKLR (0.43) | PKLRTRPA1ADAMTS4MMP13APAF1 | |
| SCHEMBL4621060 | 0.80 | ADAMTS4 (0.53) | ADAMTS4MMP13APAF1MMEMMP2 | |
| SCHEMBL4619215 | 0.80 | ADAMTS4 (0.53) | ADAMTS4MMP13APAF1MMEMMP2 | |
| SCHEMBL6821970 | 0.77 | MMP2 (0.57) | MMP2MMP3CA2MMP1MMP9 | |
| SCHEMBL6821973 | 0.77 | MMP2 (0.57) | MMP2MMP3CA2MMP1MMP9 | |
| SCHEMBL10371824 | 0.76 | ALDH1A1 (0.42) | — | |
| SCHEMBL28258812 | 0.74 | ALDH1A1 (0.50) | APAF1 | |
| SCHEMBL6138235 | 0.74 | MME (0.56) | MME | |
| SCHEMBL1734649 | 0.73 | MMP2 (0.60) | ADAMTS4MMP13MMP2MMP3MMP1 | |
| SCHEMBL1734647 | 0.73 | MMP2 (0.60) | ADAMTS4MMP13MMP2MMP3MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1884230-A1 | PARAKERATOSIS INHIBITOR, PORE-SHRINKING AGENT OR AGENT FOR PREVENTING/AMELIORATING ROUGH SKIN AND EXTERNAL COMPOSITION FOR SKIN | Shiseido Company, Limited (JP) | 2008-02-06 | — | — | EP | disclosed |