Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.54 |
| ▸ | HTR2A | P28223 | 3/20 | 0.54 |
| ▸ | HTR2B | P41595 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.52 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4027212 | 0.90 | HTR2C (0.53) | HTR2CHTR2AHTR2BHTTSMN1; SMN2 | |
| SCHEMBL4029271 | 0.83 | HTR2C (0.49) | HTR2CHTR2AHTR2BHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4024343 | 0.82 | HTR2C (0.48) | HTR2CHTR2AHTR2BHTTSMN1; SMN2 | |
| SCHEMBL12781820 | 0.79 | ALDH1A1 (0.67) | HTR2CHTR2AHTR2BHTTSMN1; SMN2 | |
| SCHEMBL10169464 | 0.79 | SMN1; SMN2 (0.73) | HTTSMN1; SMN2MCHR1MEN1KMT2A | |
| SCHEMBL14221051 | 0.79 | SIGMAR1 (0.62) | HTR2CHTR2AHTR2BSIGMAR1MCHR1 | |
| SCHEMBL4023275 | 0.78 | MEN1 (0.57) | HTR2CHTR2AHTR2BSIGMAR1SLC5A7 | |
| Hydrochloric Acid SCHEMBL4623932 | 0.78 | SIGMAR1 (0.61) | HTR2CHTR2AHTR2BSIGMAR1MCHR1 | |
| SCHEMBL4028957 | 0.78 | HTR2C (0.46) | HTR2CHTR2AHTR2BHTTSMN1; SMN2 | |
| SCHEMBL3673327 | 0.77 | HIF1A (0.59) | SMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599445-B1 | COMPOUNDS HAVING ACTIVITY AT 5HT2C RECEPTOR AND USES THEREOF | GLAXO GROUP LTD (GB) | 2008-04-02 | — | — | EP | disclosed |
| US-20060205788-A1 | Compounds having activity at 5ht2c receptor and uses thereof | GLAXO GROUP LIMITED (GB) | 2006-09-14 | — | — | US | disclosed |
| EP-1599445-A1 | COMPOUNDS HAVING ACTIVITY AT 5HT2C RECEPTOR AND USES THEREOF | GLAXO GROUP LIMITED (GB) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004078718-A1 | COMPOUNDS HAVING ACTIVITY AT 5HT2C RECEPTOR AND USES THEREOF | GLAXO GROUP LIMITED (GB) | 2004-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205788-A1 | Compounds having activity at 5ht2c receptor and uses thereof | HTR2C, HTR7, HTR3C | HTR2C 1/4885HTR2A 13/4885HTR2B 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.