Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 4/20 | 0.43 |
| ▸ | CBX7 | O95931 | 1/20 | 0.40 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.40 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.40 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4621940 | 0.85 | MEN1 (0.46) | MEN1KMT2AMAPTTSHRHIF1A | |
| SCHEMBL5097655 | 0.84 | MAPT (0.46) | MEN1KMT2AMAPTTSHRHIF1A | |
| SCHEMBL4621639 | 0.79 | PDE10A (0.47) | MEN1KMT2ATSHRALDH1A1PDE10A | |
| SCHEMBL4622564 | 0.76 | KDM4E (0.37) | CYP3A4ALDH1A1PDE10A | |
| SCHEMBL5093348 | 0.73 | PKM (0.44) | MEN1KMT2AMAPT | |
| SCHEMBL5088534 | 0.73 | PLA2G2A (0.42) | MEN1KMT2AMAPTCYP1A2CYP3A4 | |
| SCHEMBL5093356 | 0.72 | PKM (0.44) | MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL5090503 | 0.72 | PLA2G2A (0.51) | MAPTALDH1A1 | |
| SCHEMBL15954474 | 0.72 | HIF1A (0.67) | MEN1KMT2AMAPTTSHRHIF1A | |
| SCHEMBL31150639 | 0.72 | HIF1A (0.67) | MEN1KMT2AMAPTTSHRHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1696924-B1 | ACIDIC QUINOLINE DERIVATIVES AND THEIR USE FOR THE PREVENTION AND/OR TREATMENT OF HYPERGLYCAEMIA-RELATED PATHOLOGIES | MERCK PATENT GMBH (DE) | 2008-03-26 | — | — | EP | claimed |