Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 13/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4622564 | 0.84 | KDM4E (0.37) | PDE10AHPGDALDH1A1PRNPIDO1 | |
| SCHEMBL4620763 | 0.81 | PDE10A (0.52) | PDE10ATSHRMEN1GAAHPGD | |
| SCHEMBL4622456 | 0.80 | ALDH1A1 (0.37) | PDE10AGAAALDH1A1IDO1CASP3 | |
| SCHEMBL4621944 | 0.79 | MEN1 (0.44) | PDE10ATSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL4620316 | 0.78 | PLA2G2A (0.47) | PDE10ATSHRCYP2C9IDO1CASP3 | |
| SCHEMBL11620577 | 0.76 | NCF1 (0.51) | PDE10AMEN1KMT2AALDH1A1 | |
| SCHEMBL4621100 | 0.76 | KDM4E (0.43) | PDE10AGAAPRNPIDO1CASP3 | |
| SCHEMBL4622162 | 0.73 | CASP3 (0.39) | PDE10ACYP2C9MEN1GAAHPGD | |
| SCHEMBL30744772 | 0.72 | ALOX15 (0.49) | PDE10ATSHRKDM4E | |
| SCHEMBL11101493 | 0.71 | BACE1 (0.47) | TSHRMEN1GAAHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1696924-B1 | ACIDIC QUINOLINE DERIVATIVES AND THEIR USE FOR THE PREVENTION AND/OR TREATMENT OF HYPERGLYCAEMIA-RELATED PATHOLOGIES | MERCK PATENT GMBH (DE) | 2008-03-26 | — | — | EP | claimed |