SCHEMBL7188581

SCHEMBL7188581

CCC1=Cc2c(-c3cccc4ccccc34)cccc2C1C[SiH]([Zr])CC1C(CC)=Cc2c(-c3cccc4ccccc34)cccc21

nearest known ligand 0.31

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
KMT2A Q03164 1/20 0.31
HTR7 P34969 1/20 0.31
SLC6A4 P31645 2/20 0.30
DRD2 P14416 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4622630 0.85 SLC6A4 (0.34) ALOX15MEN1ALDH1A1MAPTHPGD
SCHEMBL7150481 0.85 ALDH1A1 (0.32) ALOX15MEN1ALDH1A1MAPTHPGD
SCHEMBL7188940 0.83
SCHEMBL3998523 0.81 MEN1 (0.31) MEN1ALDH1A1MAPTHPGDKMT2A
SCHEMBL27559648 0.80 SLC6A4 (0.33) ALOX15MEN1ALDH1A1MAPTHPGD
SCHEMBL5859330 0.79 SLC6A4 (0.34) ALOX15MEN1ALDH1A1MAPTHPGD
SCHEMBL7187133 0.79
SCHEMBL7189480 0.79 EDNRB (0.33)
SCHEMBL8613248 0.78 SLC6A4 (0.34) ALOX15MEN1ALDH1A1MAPTHPGD
Hydrochloric Acid SCHEMBL4065888 0.76 HTR7 (0.35) ALOX15ALDH1A1MAPTHPGDHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6583227-B2 Crystalline homo/copolymers prepared using sequential or parallel metallocene dual catalyst system; broad, bimodal molecular weight distribution; biaxially oriented and non-oriented films; even stretch at low temperature EXXONMOBIL CHEMICAL PATENTS INC. 2003-06-24 US disclosed
US-20010044506-A1 Crystalline homo/copolymers prepared using sequential or parallel metallocene dual catalyst system; broad, bimodal molecular weight distribution; biaxially oriented and non-oriented films; even stretch at low temperature EXXONMOBIL CHEMICAL PATENTS INC. 2001-11-22 US disclosed