Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.39 |
| ▸ | TK1 | P04183 | 1/20 | 0.38 |
| ▸ | PDE1A | P54750 | 2/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.37 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | BRD2 | P25440 | 1/20 | 0.36 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.36 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23797830 | 0.88 | HTT (0.42) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL4796600 | 0.87 | PDE4A (0.47) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL5647 | 0.82 | ADORA2A (0.43) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL3110932 | 0.80 | PDE1A (0.53) | PDE1APDE1BPDE1CPDE2AMEN1 | |
| SCHEMBL652922 | 0.77 | MAPK1 (0.39) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL4623478 | 0.75 | KDM4E (0.38) | PDE1APDE1BPDE1CPDE2AMEN1 | |
| SCHEMBL28151874 | 0.73 | TK1 (0.50) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL4623458 | 0.72 | PDE4A (0.63) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL6251096 | 0.72 | PDE4A (0.64) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL28324506 | 0.71 | LMNA (0.41) | PDE4AADORA2APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904020-A2 | NEW SLIMMING COSMETIC COMPOSITIONS | Sederma S.A.S. (FR) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007010478-A2 | SLIMMING COSMETIC COMPOSITIONS | SEDERMA (FR) | 2007-01-25 | — | — | WO | disclosed |