SCHEMBL4623478

SCHEMBL4623478

Cc1nc2c(=O)[nH]c(=O)n(CC(C)C)c2n1CCO

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.38
NPSR1 Q6W5P4 1/20 0.38
ALDH1A1 P00352 6/20 0.37
HPGD P15428 3/20 0.37
MEN1 O00255 6/20 0.36
KMT2A Q03164 6/20 0.36
LMNA P02545 1/20 0.36
GAA P10253 1/20 0.36
PDE1A P54750 2/20 0.36
PDE1B Q01064 2/20 0.36
PDE1C Q14123 2/20 0.36
PDE2A O00408 1/20 0.36
PKM P14618 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8937183 0.83 KDM4E (0.43) KDM4ENPSR1ALDH1A1HPGDMEN1
SCHEMBL4623658 0.75 PDE4A (0.39) KDM4ENPSR1ALDH1A1MEN1KMT2A
SCHEMBL7624092 0.74 KDM4E (0.42) KDM4ENPSR1ALDH1A1HPGDMEN1
SCHEMBL1804901 0.72 KDM4E (0.41) KDM4ENPSR1ALDH1A1HPGDMEN1
SCHEMBL11292373 0.72 KDM4E (0.52) KDM4ENPSR1ALDH1A1HPGDMEN1
SCHEMBL2476718 0.71 MEN1 (0.45) KDM4ENPSR1ALDH1A1HPGDMEN1
SCHEMBL9765951 0.71 ADORA2A (0.49) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL5647 0.70 ADORA2A (0.43) KDM4ENPSR1ALDH1A1HPGDMEN1
SCHEMBL8642882 0.67 ALDH1A1 (0.43) KDM4ENPSR1ALDH1A1HPGDMEN1
SCHEMBL4796600 0.66 PDE4A (0.47) KDM4EALDH1A1HPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1904020-A2 NEW SLIMMING COSMETIC COMPOSITIONS Sederma S.A.S. (FR) 2008-04-02 EP disclosed
WO-2007010478-A2 SLIMMING COSMETIC COMPOSITIONS SEDERMA (FR) 2007-01-25 WO disclosed