Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 17/20 | 0.54 |
| ▸ | THRB | P10828 | 17/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4623917 | 0.87 | THRA (0.48) | THRATHRBESR1NR3C1PGR | |
| SCHEMBL4624544 | 0.82 | PSMB8 (0.39) | THRATHRBESR1NR3C1PGR | |
| SCHEMBL1603232 | 0.80 | KMT2A (0.42) | — | |
| SCHEMBL8875118 | 0.78 | SMN1; SMN2 (0.41) | THRBL3MBTL1 | |
| SCHEMBL4624551 | 0.75 | ALDH1A1 (0.52) | HDAC6L3MBTL1 | |
| SCHEMBL7048368 | 0.73 | MEN1 (0.45) | L3MBTL1 | |
| SCHEMBL4900331 | 0.71 | FFAR1 (0.67) | THRATHRBESR1NR3C1PGR | |
| SCHEMBL9424806 | 0.71 | CYP1A2 (0.50) | HDAC6PARP1PARP2KEAP1 | |
| SCHEMBL9425254 | 0.71 | FFAR1 (0.47) | HDAC6PARP1PARP2KEAP1 | |
| SCHEMBL4898411 | 0.71 | THRA (0.70) | THRATHRBESR1NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242622-B1 | MONITORING OLIGONUCLEOTIDE BINDING PROCESSES USING CHEMILUMINESCENCE QUENCHING | MOLECULAR LIGHT TECH RES LTD (GB) | 2008-06-18 | — | — | EP | disclosed |
| US-7169554-B2 | Monitoring oligonucleotide binding processes using chemiluminescence quenching | GEN-PROBE INCORPORATED (US) | 2007-01-30 | — | — | US | disclosed |
| US-20030082713-A1 | Monitoring oligonucleotide binding processes using chemiluminescence quenching | THIRD WAVE TECHNOLOGIES, INC. | 2003-05-01 | — | — | US | disclosed |