Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 9/20 | 0.37 |
| ▸ | THRB | P10828 | 9/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4623903 | 0.82 | THRA (0.54) | THRATHRBESR1NR3C1PGR | |
| SCHEMBL4623917 | 0.81 | THRA (0.48) | THRATHRBNPC1RAB9AKMT2A | |
| Trifluoromethanesulfonic Acid SCHEMBL4624488 | 0.79 | PSMB8 (0.34) | PSMB8PSMB5 | |
| SCHEMBL4624551 | 0.78 | ALDH1A1 (0.52) | KMT2ASMN1; SMN2HDAC3HDAC4HDAC1 | |
| SCHEMBL4163816 | 0.75 | PSMB8 (0.39) | PSMB8PSMB5NPC1RAB9AKMT2A | |
| SCHEMBL3143334 | 0.75 | KDM4E (0.44) | KMT2ASMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL7118784 | 0.74 | KDM4E (0.40) | KMT2ASMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL5182384 | 0.72 | PSMB8 (0.40) | PSMB8PSMB5NPC1RAB9AKMT2A | |
| SCHEMBL436079 | 0.72 | TDP1 (0.54) | PSMB8PSMB5NPC1KMT2AHDAC2 | |
| SCHEMBL7589928 | 0.72 | PSMB8 (0.33) | PSMB8PSMB5KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242622-B1 | MONITORING OLIGONUCLEOTIDE BINDING PROCESSES USING CHEMILUMINESCENCE QUENCHING | MOLECULAR LIGHT TECH RES LTD (GB) | 2008-06-18 | — | — | EP | disclosed |
| US-7169554-B2 | Monitoring oligonucleotide binding processes using chemiluminescence quenching | GEN-PROBE INCORPORATED (US) | 2007-01-30 | — | — | US | disclosed |
| US-20030082713-A1 | Monitoring oligonucleotide binding processes using chemiluminescence quenching | THIRD WAVE TECHNOLOGIES, INC. | 2003-05-01 | — | — | US | disclosed |