Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 5/20 | 0.37 |
| ▸ | MMP9 | P14780 | 5/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 4/20 | 0.36 |
| ▸ | MMP8 | P22894 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1980043 | 0.94 | MMP2 (0.42) | TDP1MMP2MMP9MMP3MMP13 | |
| SCHEMBL4642996 | 0.88 | LMNA (0.38) | TDP1MMP2MMP9MMP3MMP13 | |
| SCHEMBL11583297 | 0.80 | MMP14 (0.36) | MMP13 | |
| SCHEMBL11581950 | 0.80 | PYGB (0.31) | — | |
| SCHEMBL11580974 | 0.79 | LMNA (0.46) | TDP1MMP2MMP9MMP3LMNA | |
| SCHEMBL6331007 | 0.75 | TDP1 (0.40) | TDP1MMP2MMP9MMP3MMP13 | |
| SCHEMBL5272059 | 0.75 | LMNA (0.43) | MMP2MMP9MMP3MMP13MMP8 | |
| SCHEMBL6691265 | 0.73 | SMN1; SMN2 (0.46) | TDP1MMP2MMP9MMP3HSD17B10 | |
| SCHEMBL4620466 | 0.73 | TDP1 (0.36) | TDP1MMP2MMP9MMP3MMP13 | |
| SCHEMBL6692266 | 0.72 | LMNA (0.40) | TDP1MMP2MMP9MMP3MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1883454-A2 | AGENT FOR PERMANENT HAIR WAVING CONTAINING HETEROCYCLIC MERCAPTO COMPOUND | Showa Denko K.K. (JP) | 2008-02-06 | — | — | EP | disclosed |
| WO-2006126729-A2 | AGENT FOR PERMANENT HAIR WAVING CONTAINING HETEROCYCLIC MERCAPTO COMPOUND | SHOWA DENKO K.K. (JP) | 2006-11-30 | — | — | WO | disclosed |
| EP-0309310-A1 | Enzymatic system, process for its preparation and its use, especially in the preparation of D-para-hydroxyphenyl glycine | SOCIETE FRANCAISE HOECHST Société anonyme dite: (FR) | 1989-03-29 | — | — | EP | disclosed |