Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 3/20 | 0.32 |
| ▸ | MMP9 | P14780 | 3/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 2/20 | 0.31 |
| ▸ | MMP13 | P45452 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4623915 | 0.88 | TDP1 (0.38) | LMNATDP1MMP2MMP9MMP3 | |
| SCHEMBL1980043 | 0.86 | MMP2 (0.42) | LMNATDP1MMP2MMP9MMP3 | |
| SCHEMBL11580974 | 0.82 | LMNA (0.46) | LMNATDP1KDM4EALDH1A1CYP3A4 | |
| Propane SCHEMBL27722448 | 0.80 | LMNA (0.44) | LMNATDP1KDM4EALDH1A1CYP3A4 | |
| Ethane SCHEMBL28768900 | 0.78 | LMNA (0.43) | LMNATDP1KDM4EALDH1A1CYP3A4 | |
| SCHEMBL11583297 | 0.76 | MMP14 (0.36) | ALDH1A1MMP13 | |
| SCHEMBL11581950 | 0.75 | PYGB (0.31) | — | |
| SCHEMBL2138557 | 0.73 | PDE7A (0.46) | LMNATDP1KDM4EALDH1A1CYP3A4 | |
| SCHEMBL9334279 | 0.73 | LMNA (0.46) | LMNAKDM4EALDH1A1CYP3A4GABRB3 | |
| SCHEMBL4618645 | 0.72 | KDM4E (0.32) | LMNAKDM4EALDH1A1CYP3A4GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1883454-A2 | AGENT FOR PERMANENT HAIR WAVING CONTAINING HETEROCYCLIC MERCAPTO COMPOUND | Showa Denko K.K. (JP) | 2008-02-06 | — | — | EP | disclosed |
| WO-2006126729-A2 | AGENT FOR PERMANENT HAIR WAVING CONTAINING HETEROCYCLIC MERCAPTO COMPOUND | SHOWA DENKO K.K. (JP) | 2006-11-30 | — | — | WO | disclosed |