Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 4/20 | 0.47 |
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL491753 | 0.89 | MTNR1A (0.46) | HRH1HTR2ATBXAS1GRM2GRM3 | |
| SCHEMBL11902127 | 0.87 | RIPK1 (0.44) | — | |
| SCHEMBL8606150 | 0.82 | ALDH1A1 (0.37) | MTNR1AMTNR1BCNR1CNR2 | |
| SCHEMBL5692956 | 0.80 | TBXAS1 (0.63) | HRH1HTR2ATBXAS1GRM2GRM3 | |
| SCHEMBL8494372 | 0.80 | HRH1 (0.54) | HRH1HTR2ATBXAS1GRM2GRM3 | |
| SCHEMBL18761314 | 0.80 | HRH1 (0.54) | HRH1HTR2ATBXAS1GRM2GRM3 | |
| SCHEMBL4219820 | 0.79 | HRH1 (0.57) | HRH1HTR2ATBXAS1GRM2GRM3 | |
| Hydrochloric Acid SCHEMBL2861647 | 0.79 | TBXAS1 (0.61) | HRH1HTR2ATBXAS1GRM2GRM3 | |
| SCHEMBL26914641 | 0.78 | RIPK1 (0.46) | — | |
| SCHEMBL18761347 | 0.77 | HRH1 (0.55) | HRH1HTR2ATBXAS1GRM2GRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1444239-B1 | HIGH REFRACTIVE INDEX AROMATIC-BASED SILYL MONOMERS | BAUSCH & LOMB (US) | 2008-12-24 | — | — | EP | claimed |
| EP-1448571-B1 | HIGH REFRACTIVE INDEX AROMATIC-BASED SILOXANE MONOFUNCTIONAL MACROMONOMERS | BAUSCH & LOMB (US) | 2008-05-21 | — | — | EP | claimed |