Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7656090 | 0.89 | HTT (0.44) | MMP2MMP14HSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL7714315 | 0.86 | MAPT (0.50) | MAPTPOLBHSP90AA1MMP2MMP14 | |
| SCHEMBL4622978 | 0.82 | MAPT (0.46) | MAPTPOLBHSP90AA1MMP2MMP14 | |
| SCHEMBL8148126 | 0.81 | MAPT (0.41) | MAPTPOLBHSP90AA1HSD17B10NR4A1 | |
| SCHEMBL8371684 | 0.81 | MMP2 (0.41) | MAPTPOLBHSP90AA1MMP2SMN1; SMN2 | |
| SCHEMBL8371687 | 0.80 | LMNA (0.38) | MAPTKDM4ESMN1; SMN2CRHBPCRHR2 | |
| SCHEMBL7551329 | 0.78 | MAPT (0.42) | MAPTPOLBHSP90AA1MMP2MMP14 | |
| SCHEMBL6849207 | 0.78 | MAPT (0.42) | MAPTPOLBHSP90AA1MMP2MMP14 | |
| SCHEMBL4623369 | 0.77 | MAPT (0.41) | MAPTPOLBHSP90AA1MMP2MMP14 | |
| SCHEMBL8137368 | 0.77 | MAPT (0.38) | MAPTPOLBHSP90AA1NR4A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0905169-B1 | Precursors of polybenzoxazoles and polybenzothiazoles | INFINEON TECHNOLOGIES AG (DE) | 2008-04-02 | — | — | EP | disclosed |
| EP-0918050-B1 | Bis-o-amino(thio)phenols and their preparation | INFINEON TECHNOLOGIES AG (DE) | 2001-12-12 | — | — | EP | disclosed |
| US-6156902-A | Bis-o-amino (thio) phenols, and their preparation | INFINEON TECHNOLOGIES AG (DE) | 2000-12-05 | — | — | US | disclosed |
| EP-0918050-A1 | Bis-o-amino(thio)phenols and their preparation | SIEMENS AKTIENGESELLSCHAFT (DE) | 1999-05-26 | — | — | EP | disclosed |
| EP-0905169-A2 | Precursors of polybenzoxazoles and polybenzothiazoles | SIEMENS AKTIENGESELLSCHAFT (DE) | 1999-03-31 | — | — | EP | disclosed |