Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | RXRB | P28702 | 2/20 | 0.36 |
| ▸ | RXRG | P48443 | 2/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8371684 | 0.90 | MMP2 (0.41) | HTTHPGDLMNASMN1; SMN2NPC1 | |
| SCHEMBL8371687 | 0.89 | LMNA (0.38) | HTTHPGDLMNASMN1; SMN2NPC1 | |
| SCHEMBL4624402 | 0.89 | MAPT (0.40) | SMN1; SMN2RAB9AHSD17B10THRBTSHR | |
| SCHEMBL7658168 | 0.86 | HPGD (0.50) | HTTHPGDLMNAPARP15PARP10 | |
| SCHEMBL7654088 | 0.78 | PARP10 (0.58) | ALDH1A1PARP15PARP10RXRARXRB | |
| SCHEMBL7651725 | 0.77 | HPGD (0.42) | HTTHPGDLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7714315 | 0.77 | MAPT (0.50) | HTTHPGDLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL24407671 | 0.74 | HPGD (0.63) | HTTHPGDLMNAPARP15PARP10 | |
| SCHEMBL4623369 | 0.73 | MAPT (0.41) | HTTHPGDLMNASMN1; SMN2NPC1 | |
| SCHEMBL4622978 | 0.73 | MAPT (0.46) | HTTHPGDLMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0905170-B1 | Polybenzoxazoles and polybenzothiazoles precursors | QIMONDA AG (DE) | 2013-10-30 | — | — | EP | disclosed |
| US-6437178-B2 | REACTING A HALOGENATED BENZENE COMPOUND WITH NITRO(THIO)PHENOL; REDUCTION | INFINEON TECHNOLOGIES AG (DE) | 2002-08-20 | — | — | US | disclosed |
| US-20010056203-A1 | O-aminophenolcarboxylic acid and o-aminothiophenolcarboxylic acid | SIEMENS AKTIENGESELLSCHAFT | 2001-12-27 | — | — | US | disclosed |
| EP-0905123-B1 | o-amino(thio)phenol-carboxylic acids and their preparation | INFINEON TECHNOLOGIES AG (DE) | 2001-12-12 | — | — | EP | disclosed |
| US-6310238-B1 | INTERMEDIATES FOR THE PREPARATION OF POLYBENZOXAZOLES AND POLYBENZOTHIAZOLES | SIEMENS AKTIENGESELLSCHAFT (DE) | 2001-10-30 | — | — | US | disclosed |
| EP-0905123-A1 | o-amino(thio)phenol-carboxylic acids and their preparation | SIEMENS AKTIENGESELLSCHAFT (DE) | 1999-03-31 | — | — | EP | disclosed |
| EP-0905170-A2 | Polybenzoxazoles and polybenzothiazoles precursors | SIEMENS AKTIENGESELLSCHAFT (DE) | 1999-03-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010056203-A1 | O-aminophenolcarboxylic acid and o-aminothiophenolcarboxylic acid | TPMT, PAH, AADAT | HTT 2766/4885HPGD 1718/4885LMNA 4771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.