Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | FPR1 | P21462 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | LIG1 | P18858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7091735 | 0.74 | SLC6A3 (0.40) | SLC6A3SLC6A2SLC6A4HTR3ARAB9A | |
| SCHEMBL17603850 | 0.71 | SLC6A3 (0.41) | SLC6A3SLC6A2SLC6A4HTR3AALDH1A1 | |
| SCHEMBL12549830 | 0.71 | SLC6A3 (0.45) | SLC6A3SLC6A2SLC6A4HTR3ARAB9A | |
| SCHEMBL1069753 | 0.69 | SLC6A3 (0.48) | SLC6A3SLC6A2SLC6A4HTR3AALDH1A1 | |
| Hydrazine SCHEMBL17603742 | 0.69 | SLC6A3 (0.39) | SLC6A3SLC6A2SLC6A4HTR3ARAB9A | |
| SCHEMBL4622829 | 0.69 | SRD5A1 (0.46) | SLC6A3SLC6A2SLC6A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL10965883 | 0.67 | DRD2 (0.47) | — | |
| SCHEMBL8442229 | 0.67 | SLC6A3 (0.43) | SLC6A3SLC6A2SLC6A4HTR3ARAB9A | |
| SCHEMBL25367907 | 0.67 | NOS3 (0.40) | SLC6A3SLC6A2SLC6A4HTR3AALDH1A1 | |
| SCHEMBL22201142 | 0.67 | TP53 (0.51) | SLC6A3SLC6A2SLC6A4HTR3AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328275-B1 | SUBSTITUTED 4,5-DIHYDRO-1,2,4-TRIAZIN-3-ONES, 1,2,4-TRIAZIN-3-ONES, AND THEIR USE AS FUNGICIDES AND INSECTICIDES | DOW AGROSCIENCES LLC (US) | 2008-05-07 | — | — | EP | disclosed |
| US-6995157-B2 | Substituted 4,5-dihydro-1,2,4-triazin-3-ones, 1,2,4-triazin-3-ones, and their use as fungicides and insecticides | DOW AGROSCIENCES LLC (US) | 2006-02-07 | — | — | US | disclosed |
| EP-1328275-A4 | SUBSTITUTED 4,5-DIHYDRO-1,2,4-TRIAZIN-3-ONES, 1,2,4-TRIAZIN-3-ONES, AND THEIR USE AS FUNGICIDES AND INSECTICIDES | DOW AGROSCIENCES LLC (US) | 2004-03-10 | — | — | EP | disclosed |
| US-20040019209-A1 | Substituted 4,5-dihydro-1,2,4-triazin-3-ones,1,2,4-triazin-3-ones, and their use as fungicides and insecticides | DOW AGROSCIENCES LLC | 2004-01-29 | — | — | US | disclosed |
| EP-1328275-A2 | SUBSTITUTED 4,5-DIHYDRO-1,2,4-TRIAZIN-3-ONES, 1,2,4-TRIAZIN-3-ONES, AND THEIR USE AS FUNGICIDES AND INSECTICIDES | Dow AgroSciences LLC (US) | 2003-07-23 | — | — | EP | disclosed |
| WO-2002056682-A2 | SUBSTITUTED 4,5-DIHYDRO-1,2,4-TRIAZIN-3-ONES, 1,2,4-TRIAZIN-3-ONES, AND THEIR USE AS FUNGICIDES AND INSECTICIDES | DOW AGROSCIENCES LLC (US) | 2002-07-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040019209-A1 | Substituted 4,5-dihydro-1,2,4-triazin-3-ones,1,2,4-triazin-3-ones, and their use as fungicides and insecticides | DDT, CYP4B1, CYP4X1 | SLC6A3 502/4885SLC6A2 1326/4885SLC6A4 914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.