SCHEMBL4625643

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4627176	0.90	TSHR (0.39)	ALDH1A1CYP4F2CYP4A11TSHRTDP1
	SCHEMBL234767	0.86	TSHR (0.42)	ALDH1A1CYP4F2CYP4A11TSHRTDP1
	SCHEMBL4626651	0.82	EGFR (0.35)	ALDH1A1CYP4F2CYP4A11TSHRTDP1
	SCHEMBL6908939	0.82	TSHR (0.50)	ALDH1A1CYP4F2CYP4A11TSHRL3MBTL1
	SCHEMBL4628503	0.81	TSHR (0.55)	ALDH1A1TSHRTDP1L3MBTL1MAPK1
	SCHEMBL4627917	0.81	PPARA (0.51)	ALDH1A1TSHRMAPK1CYP3A4TP53
	SCHEMBL4627078	0.80	CRHBP (0.37)	ALDH1A1CYP4F2CYP4A11TSHRMAPK1
	SCHEMBL4627369	0.79	METAP2 (0.41)	ALDH1A1CYP4F2CYP4A11TSHRCA2
	SCHEMBL4627132	0.76	SERPINE1 (0.34)	ALDH1A1CYP4F2CYP4A11TSHRCYP3A4
	SCHEMBL4628066	0.76	SERPINE1 (0.34)	SERPINE1GABRPGABRDGABRA1GABRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.