SCHEMBL234767

SCHEMBL234767

CCc1ccc(C(=O)OCC(C)(C)C)c(C(=O)OCC(C)(C)C)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.42
CYP4F2 P78329 1/20 0.41
CYP4A11 Q02928 1/20 0.41
GABRA1 P14867 2/20 0.40
GABRB2 P47870 2/20 0.40
ALDH1A1 P00352 3/20 0.40
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA7 P43166 2/20 0.39
CA9 Q16790 2/20 0.39
CA14 Q9ULX7 2/20 0.39
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
MAPK1 P28482 2/20 0.37
TP53 P04637 1/20 0.37
CYP3A4 P08684 1/20 0.37
GABRP O00591 1/20 0.36
GABRD O14764 1/20 0.36
GABRB1 P18505 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6908939 0.95 TSHR (0.50) TSHRCYP4F2CYP4A11GABRA1GABRB2
SCHEMBL4627078 0.93 CRHBP (0.37) TSHRCYP4F2CYP4A11GABRA1GABRB2
SCHEMBL4627369 0.92 METAP2 (0.41) TSHRCYP4F2CYP4A11GABRA1GABRB2
SCHEMBL4628503 0.90 TSHR (0.55) TSHRALDH1A1TDP1L3MBTL1MAPK1
SCHEMBL4625643 0.86 ALDH1A1 (0.38) TSHRCYP4F2CYP4A11GABRA1GABRB2
SCHEMBL4627176 0.85 TSHR (0.39) TSHRCYP4F2CYP4A11GABRA1GABRB2
SCHEMBL4627917 0.84 PPARA (0.51) TSHRALDH1A1MAPK1TP53CYP3A4
SCHEMBL4627095 0.82 TSHR (0.62) TSHRCYP4F2CYP4A11GABRA1GABRB2
SCHEMBL234031 0.82 SERPINE1 (0.40) TSHRGABRA1GABRB2ALDH1A1CA12
SCHEMBL7639514 0.81 TSHR (0.43) TSHRGABRA1GABRB2ALDH1A1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3645625-B1 HIGH STIFFNESS POLYPROPYLENE IMPACT COPOLYMER EXXONMOBIL CHEMICAL PATENTS INC (US) 2024-03-27 EP disclosed
US-11732067-B2 High stiffness polypropylene impact copolymer EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-08-22 US disclosed
CN-110997795-B High stiffness polypropylene impact copolymers 埃克森美孚化学专利公司 2022-10-04 CN disclosed
US-20200140584-A1 High Stiffness Polypropylene Impact Copolymer EXXONMOBIL CHEMICAL PATENTS INC (US) 2020-05-07 US disclosed
EP-3645625-A1 HIGH STIFFNESS POLYPROPYLENE IMPACT COPOLYMER ExxonMobil Chemical Patents Inc. (US) 2020-05-06 EP disclosed
EP-3645586-A1 METHOD FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION AND A PROCESS FOR PROPYLENE POLYMERIZATION Toho Titanium Co., Ltd. (JP) 2020-05-06 EP disclosed
CN-110997795-A High stiffness polypropylene impact copolymers 埃克森美孚化学专利公司 2020-04-10 CN disclosed
EP-1283222-B9 METHOD FOR PRODUCING A SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION TOHO TITANIUM CO LTD (JP) 2019-11-13 EP disclosed
US-10364304-B2 Method for producing solid catalyst component for olefin polymerization, catalyst for olefin polymerization, and method for producing olefin polymer TOHO TITANIUM CO., LTD. (JP) 2019-07-30 US disclosed
EP-1533322-B1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST TOHO TITANIUM CO LTD (JP) 2019-05-01 EP disclosed
US-20040077488-A1 Polymerization catalyst for olefins and process for polymerization of olefins TOHO TITANIUM CO., LTD. (JP) 2004-04-22 US disclosed
US-20040072681-A1 Solid catalyst component for olefin polymerization and catalyst TOHO TITANIUM CO., LTD. (JP) 2004-04-15 US disclosed
US-6670497-B2 Dialkyl (at least one of which is a C4-8 tertiary alkyl) ester of an alkyl- or halo-substituted phthalic acid; used in an olefin polymerization catalyst TOHO TITANIUM CO., LTD. (JP) 2003-12-30 US disclosed
US-20030153454-A1 Solid catalyst ingredient and catalyst each for olefin polymerization and propylene block copolymer TOHO TITANIUM CO., LTD. (JP) 2003-08-14 US disclosed
US-20030130109-A1 Solid catalyst component and catalyst for olefins polymerization TOHO TITANIUM CO., LTD (JP) 2003-07-10 US disclosed
US-20030036594-A1 Phthalic diester derivatives and electron donors TOHO TITANIUM CO., LTD. (JP) 2003-02-20 US disclosed
EP-1283222-A1 SOLID CATALYST INGREDIENT AND CATALYST EACH FOR OLEFIN POLYMERIZATION AND PROPYLENE BLOCK COPOLYMER Toho Catalyst Co., Ltd. (JP) 2003-02-12 EP disclosed
EP-1260524-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST Toho Titanium Co., Ltd. (JP) 2002-11-27 EP disclosed
EP-1209172-A1 SOLID CATALYST COMPONENT AND CATALYST FOR OLEFIN POLYMERIZATION Toho Titanium Co., Ltd. (JP) 2002-05-29 EP disclosed
EP-1188739-A1 PHTHALIC DIESTER DERIVATIVES AND ELECTRON DONORS TOHO TITANIUM CO., LTD. (JP) 2002-03-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030036594-A1 Phthalic diester derivatives and electron donors HPD, ETFA, PPOX TSHR 4817/4885CYP4F2 220/4885CYP4A11 259/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.