Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 11/20 | 0.47 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.47 |
| ▸ | RGS12 | O14924 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL460806 | 0.78 | CCR6 (0.36) | EGFRNOX4RGS12ALDH1A1LCK | |
| SCHEMBL460805 | 0.78 | EGFR (0.54) | EGFRNOX4CA1CA2CA12 | |
| SCHEMBL11242577 | 0.73 | FFAR1 (0.50) | ALDH1A1MAPTKDM4CPPARASTING1 | |
| SCHEMBL462565 | 0.72 | HSP90AA1 (0.70) | ALDH1A1MAPTCA1CA2CA12 | |
| SCHEMBL411957 | 0.71 | CAMKK2 (0.35) | EGFRNOX4RGS12ALDH1A1LCK | |
| SCHEMBL24074190 | 0.70 | PLK1 (0.46) | KDM4CCA12CA9 | |
| SCHEMBL27770270 | 0.69 | EGFR (0.60) | EGFRNOX4RGS12ALDH1A1LCK | |
| SCHEMBL27787480 | 0.68 | EGFR (0.74) | EGFRNOX4RGS12ALDH1A1LCK | |
| Hydrochloric Acid SCHEMBL7976840 | 0.68 | KDM4E (0.51) | ALDH1A1MAPTCAMKK2TDP1 | |
| SCHEMBL27809392 | 0.68 | EGFR (0.51) | EGFRNOX4RGS12ALDH1A1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120021519-A1 | EFFICIENT INDUCTION OF PLURIPOTENT STEM CELLS USING SMALL MOLECULE COMPOUNDS | PRESIDENTS AND FELLOWS OF HARVARD COLLEGE (US) | 2012-01-26 | — | — | US | disclosed |