SCHEMBL4625871

SCHEMBL4625871

CC(C)(C)O[Si](Oc1ccc(C(c2ccccc2)c2ccccc2)c(O)c1)(c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.38
BCHE P06276 1/20 0.32
ACHE P22303 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5058761 0.98 TYR (0.36) TYRBCHEACHE
SCHEMBL5053957 0.96 TYR (0.34) TYRBCHEACHE
SCHEMBL5061159 0.92 TYR (0.41) TYRBCHEACHE
SCHEMBL5053960 0.92 TYR (0.39) TYRBCHEACHE
SCHEMBL5051777 0.90 BCHE (0.41) TYRBCHEACHE
SCHEMBL5584056 0.71 TYR (0.55) TYRBCHEACHE
SCHEMBL50738 0.70 TYR (0.54) TYRBCHEACHE
SCHEMBL14230792 0.70 MAPT (0.41)
SCHEMBL4625644 0.70 NR1H2 (0.35)
SCHEMBL5677734 0.69 LMNA (0.51) TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1401851-B8 TWO-STAGE PROTECTIVE GROUPS FOR THE SYNTHESIS OF BIOPOLYMERS FEBIT HOLDING GMBH (DE) 2008-09-10 EP disclosed
EP-1401851-B1 TWO-STAGE PROTECTIVE GROUPS FOR THE SYNTHESIS OF BIOPOLYMERS FEBIT BIOTECH GMBH (DE) 2008-07-02 EP disclosed
US-7355036-B2 Two-stage protective groups for the synthesis of biopolymers FEBIT AG (DE) 2008-04-08 US disclosed
US-20040197851-A1 Two-stage protective groups for the synthesis of biopolymers MR. CHRISTOPHER SEAGON, ESQ. (DE) 2004-10-07 US disclosed
EP-1401851-A1 TWO-STAGE PROTECTIVE GROUPS FOR THE SYNTHESIS OF BIOPOLYMERS Febit AG (DE) 2004-03-31 EP disclosed
WO-2003004510-A1 TWO-STAGE PROTECTIVE GROUPS FOR THE SYNTHESIS OF BIOPOLYMERS FEBIT AG (DE) 2003-01-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040197851-A1 Two-stage protective groups for the synthesis of biopolymers CTRB2, OGG1, CPB2 TYR 1545/4885BCHE 588/4885ACHE 1054/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.