SCHEMBL4625644

SCHEMBL4625644

CC(C)(C)O[Si](Oc1ccc(C(O)(c2ccc(O[Si](OC(C)(C)C)(c3ccccc3)c3ccccc3)cc2)c2ccc(O[Si](OC(C)(C)C)(c3ccccc3)c3ccccc3)cc2)cc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 2/20 0.35
NR1H3 Q13133 2/20 0.35
CYP19A1 P11511 3/20 0.35
AHR P35869 2/20 0.35
CYP3A4 P08684 2/20 0.35
CYP3A5 P20815 2/20 0.35
MAPT P10636 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ACSS2 Q9NR19 5/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SLC2A1 P11166 1/20 0.31
ALDH1A1 P00352 1/20 0.31
ALOX15 P16050 1/20 0.31
MEN1 O00255 1/20 0.31
RAB9A P51151 1/20 0.31
KMT2A Q03164 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4625906 0.98 CYP19A1 (0.37) NR1H2NR1H3CYP19A1AHRCYP3A4
SCHEMBL4625813 0.98 CYP19A1 (0.37) NR1H2NR1H3CYP19A1AHRCYP3A4
SCHEMBL4626920 0.94 AHR (0.43) CYP19A1AHRACSS2SMN1; SMN2ALDH1A1
SCHEMBL4624707 0.94 AHR (0.43) CYP19A1AHRACSS2SMN1; SMN2ALDH1A1
SCHEMBL4624733 0.93 AHR (0.42) CYP19A1AHRACSS2SMN1; SMN2KMT2A
SCHEMBL4626091 0.81 ALDH1A1 (0.35) MAPTTDP1ALDH1A1KMT2A
SCHEMBL4625876 0.80 ELANE (0.49)
SCHEMBL4627027 0.79 KIF11 (0.41) AHRTDP1SMN1; SMN2ALDH1A1ALOX15
SCHEMBL4627743 0.79 ELANE (0.51) TDP1ALDH1A1
SCHEMBL14230792 0.76 MAPT (0.41) NR1H2CYP19A1CYP3A4CYP3A5MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1401851-B1 TWO-STAGE PROTECTIVE GROUPS FOR THE SYNTHESIS OF BIOPOLYMERS FEBIT BIOTECH GMBH (DE) 2008-07-02 EP disclosed
US-7355036-B2 Two-stage protective groups for the synthesis of biopolymers FEBIT AG (DE) 2008-04-08 US disclosed
US-20040197851-A1 Two-stage protective groups for the synthesis of biopolymers MR. CHRISTOPHER SEAGON, ESQ. (DE) 2004-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040197851-A1 Two-stage protective groups for the synthesis of biopolymers CTRB2, OGG1, CPB2 NR1H2 4755/4885NR1H3 4816/4885CYP19A1 3284/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.