Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2971870 | 0.78 | MAPT (0.37) | TP53MAPTESR1ESR2TSHR | |
| SCHEMBL2595602 | 0.70 | MAPT (0.38) | MAPTESR1ESR2TSHRKDM4E | |
| SCHEMBL3889977 | 0.70 | TP53 (0.41) | TP53MAPTESR1ESR2TSHR | |
| SCHEMBL8464698 | 0.70 | MAPT (0.33) | MAPTESR1ESR2 | |
| SCHEMBL21061710 | 0.70 | MAPT (0.33) | MAPTESR1ESR2 | |
| SCHEMBL988676 | 0.67 | NR1H2 (0.43) | TP53MAPTESR1ESR2TSHR | |
| SCHEMBL31054141 | 0.67 | MAPT (0.35) | MAPTESR1ESR2TSHRKDM4E | |
| SCHEMBL2974829 | 0.65 | TRPA1 (0.35) | TP53MAPTESR1ESR2KDM4E | |
| SCHEMBL2444645 | 0.65 | ESR1 (0.56) | TP53MAPTESR1ESR2TSHR | |
| SCHEMBL28545159 | 0.65 | ALDH1A1 (0.42) | MAPTESR1ESR2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108358812-B | Amine-containing transfection reagents and methods of making and using same | 生命技术公司 | 2021-05-11 | — | — | CN | disclosed |
| EP-1448571-B1 | HIGH REFRACTIVE INDEX AROMATIC-BASED SILOXANE MONOFUNCTIONAL MACROMONOMERS | BAUSCH & LOMB (US) | 2008-05-21 | — | — | EP | disclosed |
| US-7022749-B2 | High refractive index aromatic-based siloxane difunctional macromonomers | BAUSCH & LOMB INCORPORATED (US) | 2006-04-04 | — | — | US | disclosed |
| US-7009024-B2 | High refractive index aromatic-based siloxane difunctional macromonomers | BAUSCH & LOMB INCORPORATED (US) | 2006-03-07 | — | — | US | disclosed |
| US-7005494-B2 | High refractive index aromatic-based siloxane monofunctional macromonomers | BAUSCH & LOMB INCORPORATED (US) | 2006-02-28 | — | — | US | disclosed |
| US-6992162-B2 | High refractive index aromatic-based siloxane monofunctional macromonomers | BAUSCH & LOMB INCORPORATED (US) | 2006-01-31 | — | — | US | disclosed |
| US-6989430-B2 | High refractive index aromatic-based siloxane monofunctional macromonomers | BAUSCH & LOMB INCORPORATED (US) | 2006-01-24 | — | — | US | disclosed |
| US-6906162-B2 | High refractive index aromatic-based siloxane monofunctional macromonomers | BAUSCH & LOMB INCORPORATED (US) | 2005-06-14 | — | — | US | disclosed |
| US-20050085611-A1 | High refractive index aromatic-based siloxane difunctional macromonomers | BAUSCH & LOMB MEXICO, S.A. DE C.V. (MX) | 2005-04-21 | — | — | US | disclosed |
| US-6881808-B2 | High refractive index aromatic-based siloxane difunctional macromonomers | BAUSCH & LOMB INCORPORATED (US) | 2005-04-19 | — | — | US | disclosed |
| EP-1448571-A1 | HIGH REFRACTIVE INDEX AROMATIC-BASED SILOXANE MONOFUNCTIONAL MACROMONOMERS | BAUSCH & LOMB INCORPORATED (US) | 2004-08-25 | — | — | EP | disclosed |
| EP-1446409-A1 | HIGH REFRACTIVE INDEX AROMATIC-BASED SILOXANE DIFUNCTIONAL MACROMONOMERS | BAUSCH & LOMB INCORPORATED (US) | 2004-08-18 | — | — | EP | disclosed |
| US-6730767-B2 | OPTICAL TRANSPARENT; BIOCOMPATIBLE MEDICAL EQUIPMENT | BAUSCH & LOMB INCORPORATED | 2004-05-04 | — | — | US | disclosed |
| US-6723816-B2 | OPTICS; RADIATION TRANSPARENT | BAUSCH & LOMB INCORPORATED | 2004-04-20 | — | — | US | disclosed |
| WO-2003040154-A1 | HIGH REFRACTIVE INDEX AROMATIC-BASED SILOXANE DIFUNCTIONAL MACROMONOMERS | BAUSCH & LOMB INCORPORATED (US) | 2003-05-15 | — | — | WO | disclosed |
| WO-2003040155-A1 | HIGH REFRACTIVE INDEX AROMATIC-BASED SILOXANE MONOFUNCTIONAL MACROMONOMERS | BAUSCH & LOMB INCORPORATED (US) | 2003-05-15 | — | — | WO | disclosed |