Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | FNTA | P49354 | 1/20 | 0.49 |
| ▸ | FNTB | P49356 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | ICMT | O60725 | 2/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6287419 | 0.88 | HTR2A (0.58) | ALDH1A1HPGDMAPTKDM4EMEN1 | |
| SCHEMBL25139531 | 0.84 | HTR2A (0.58) | ALDH1A1HPGDMAPTKDM4EMEN1 | |
| SCHEMBL10123846 | 0.83 | ICMT (0.66) | MAPTHTR2ANR4A2ICMTNR3C1 | |
| SCHEMBL25139540 | 0.82 | HTR2A (0.55) | ALDH1A1HPGDMAPTKDM4EMEN1 | |
| SCHEMBL9012524 | 0.82 | ALDH1A1 (0.63) | ALDH1A1HPGDMAPTKDM4EMEN1 | |
| SCHEMBL14564356 | 0.81 | NR4A2 (0.58) | ALDH1A1HPGDMAPTKDM4EMEN1 | |
| SCHEMBL14823139 | 0.79 | PKM (0.70) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL20119825 | 0.79 | HTR2A (0.63) | HPGDMAPTSMN1; SMN2HTR2ANR4A2 | |
| SCHEMBL12233833 | 0.79 | HTR2A (0.67) | MAPTMEN1KMT2AHTR2ANR4A2 | |
| SCHEMBL125249 | 0.78 | MEN1 (1.00) | ALDH1A1HPGDMAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1529776-B1 | Amino acid derivatives and sweetening agent | AJINOMOTO KK (JP) | 2008-03-05 | — | — | EP | disclosed |
| US-7244462-B2 | Amino acid derivative and sweetening agent | AJINOMOTO CO., INC. (JP) | 2007-07-17 | — | — | US | disclosed |
| US-20050118317-A1 | Novel amino acid derivative and sweetening agent | AJINOMOTO CO., INC. (JP) | 2005-06-02 | — | — | US | disclosed |
| EP-1529776-A2 | Amino acid derivatives and sweetening agent | Ajinomoto Co., Inc. (JP) | 2005-05-11 | — | — | EP | disclosed |