Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28758480 | 0.79 | KDM4E (0.41) | KDM4ESMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL3731249 | 0.71 | ALOX5 (0.35) | KDM4ESMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL3743379 | 0.71 | DRD2 (0.39) | KDM4ESMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL4625872 | 0.70 | KDM4E (0.33) | KDM4ESMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL11886360 | 0.70 | MAOA (0.37) | KDM4ESMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL27756076 | 0.69 | ALDH1A1 (0.37) | KDM4EMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL19267117 | 0.69 | KDM4E (0.44) | KDM4ESMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL17399090 | 0.69 | MYLK (0.38) | KDM4ESMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL4015059 | 0.69 | ALDH1A1 (0.35) | KDM4ESMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL30986852 | 0.68 | MAOA (0.41) | KDM4ESMN1; SMN2ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432388-B1 | AGENT FOR COLOURING FIBRES CONTAINING KERATIN | HENKEL AG & CO KGAA (DE) | 2008-06-18 | — | — | EP | claimed |
| EP-1200050-B1 | DYEING AGENT FOR KERATINOUS FIBRES | HENKEL KGAA (DE) | 2004-09-22 | — | — | EP | claimed |
| US-6755872-B1 | ALDEHYDE OR KETONE AND NITROAMINE HETEROAROMATICS; NO OXIDING AGENT REQUIRED; COLORFASTNESS; GREY COVERAGE; COLOR DEPTH | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-06-29 | — | — | US | claimed |
| CN-1681470-A | Agent for dyeing keratinous fibres | HENKEL KGAA (DE) | 2005-10-12 | — | — | CN | disclosed |
| US-6755872-B1 | ALDEHYDE OR KETONE AND NITROAMINE HETEROAROMATICS; NO OXIDING AGENT REQUIRED; COLORFASTNESS; GREY COVERAGE; COLOR DEPTH | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-06-29 | — | — | US | disclosed |