Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | COMT | P21964 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL889379 | 0.87 | MGLL (0.48) | SMN1; SMN2KDM4EALDH1A1NOTUM | |
| SCHEMBL13575372 | 0.85 | SMN1; SMN2 (0.55) | SMN1; SMN2DDB1CRBNCOMTKDM4E | |
| SCHEMBL12438375 | 0.84 | F2 (0.44) | SMN1; SMN2COMTKDM4EALDH1A1CYP1A2 | |
| SCHEMBL10140801 | 0.82 | ALDH1A1 (0.38) | SMN1; SMN2KDM4EALDH1A1HPGDKCNH2 | |
| SCHEMBL25016644 | 0.75 | HDAC4 (0.43) | SMN1; SMN2COMTKDM4EALDH1A1HPGD | |
| SCHEMBL7861231 | 0.75 | SMN1; SMN2 (0.60) | SMN1; SMN2DDB1CRBNCOMTKDM4E | |
| SCHEMBL10059763 | 0.74 | ALDH1A1 (0.59) | SMN1; SMN2DDB1CRBNIDH1COMT | |
| SCHEMBL22185246 | 0.74 | BIRC5 (0.41) | SMN1; SMN2ALDH1A1NOTUM | |
| SCHEMBL22185248 | 0.74 | PLA2G4A (0.48) | SMN1; SMN2ALDH1A1KCNH2 | |
| SCHEMBL10059829 | 0.73 | SMN1; SMN2 (0.41) | SMN1; SMN2DDB1CRBNNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539155-B1 | STABLE CREAM PREPARATIONS OF PHENYL-PYRIDONE COMPOUNDS FOR TOPICAL APPLICATION | MEPHA AG (CH) | 2008-04-02 | — | — | EP | claimed |
| US-20060039931-A1 | Stable cream preparations of phenyl-pyridone compounds for topical application | MEPHA AG (CH) | 2006-02-23 | — | — | US | claimed |
| US-11279733-B2 | Peptide antibiotics | THE UNIVERSITY OF QUEENSLAND (AU) | 2022-03-22 | — | — | US | disclosed |
| US-20200361994-A1 | PEPTIDE ANTIBIOTICS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2020-11-19 | — | — | US | disclosed |
| EP-1539155-B1 | STABLE CREAM PREPARATIONS OF PHENYL-PYRIDONE COMPOUNDS FOR TOPICAL APPLICATION | MEPHA AG (CH) | 2008-04-02 | — | — | EP | disclosed |
| US-20060039931-A1 | Stable cream preparations of phenyl-pyridone compounds for topical application | MEPHA AG (CH) | 2006-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060039931-A1 | Stable cream preparations of phenyl-pyridone compounds for topical application | PNPO, APOB, PLPBP | SMN1; SMN2 2468/4885DDB1 1699/4885CRBN 4243/4885 |
| US-20200361994-A1 | PEPTIDE ANTIBIOTICS | NGLY1, VIP, PEPD | SMN1; SMN2 4207/4885DDB1 1201/4885CRBN 4103/4885 |
| US-11279733-B2 | Peptide antibiotics | NGLY1, VIP, PEPD | SMN1; SMN2 4207/4885DDB1 1201/4885CRBN 4103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.