Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | APEX1 | P27695 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | MYC | P01106 | 4/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1260115 | 0.89 | POLB (0.53) | POLBAPEX1TDP1L3MBTL1MYC | |
| SCHEMBL31310197 | 0.77 | L3MBTL1 (0.64) | POLBAPEX1TDP1L3MBTL1MYC | |
| SCHEMBL1259232 | 0.77 | ALDH1A1 (0.49) | POLBAPEX1TDP1L3MBTL1MYC | |
| SCHEMBL27452136 | 0.76 | L3MBTL1 (0.67) | POLBAPEX1TDP1L3MBTL1MYC | |
| SCHEMBL20689349 | 0.75 | PTGS1 (0.55) | POLBAPEX1TDP1L3MBTL1MYC | |
| Phthalic Acid SCHEMBL20659668 | 0.75 | ALDH1A1 (0.74) | POLBTDP1MYCNR4A1ALDH1A1 | |
| Phthalic Acid SCHEMBL28214902 | 0.75 | ALDH1A1 (0.74) | POLBTDP1MYCNR4A1ALDH1A1 | |
| SCHEMBL1259846 | 0.75 | MYC (0.51) | POLBMYCTSHRALDH1A1KMT2A | |
| SCHEMBL4313192 | 0.75 | ALDH1A1 (0.42) | POLBAPEX1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL1259543 | 0.75 | L3MBTL1 (0.49) | POLBAPEX1TDP1L3MBTL1MYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539155-B1 | STABLE CREAM PREPARATIONS OF PHENYL-PYRIDONE COMPOUNDS FOR TOPICAL APPLICATION | MEPHA AG (CH) | 2008-04-02 | — | — | EP | claimed |
| US-20060039931-A1 | Stable cream preparations of phenyl-pyridone compounds for topical application | MEPHA AG (CH) | 2006-02-23 | — | — | US | claimed |
| EP-1539155-B1 | STABLE CREAM PREPARATIONS OF PHENYL-PYRIDONE COMPOUNDS FOR TOPICAL APPLICATION | MEPHA AG (CH) | 2008-04-02 | — | — | EP | disclosed |
| US-20060039931-A1 | Stable cream preparations of phenyl-pyridone compounds for topical application | MEPHA AG (CH) | 2006-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060039931-A1 | Stable cream preparations of phenyl-pyridone compounds for topical application | PNPO, APOB, PLPBP | POLB 42/4885APEX1 2298/4885TDP1 222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.