Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | MPI | P34949 | 2/20 | 0.40 |
| ▸ | PHOSPHO1 | Q8TCT1 | 2/20 | 0.40 |
| ▸ | PMM2 | O15305 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1260115 | 0.83 | POLB (0.53) | ALDH1A1POLBTDP1L3MBTL1APEX1 | |
| SCHEMBL26601369 | 0.78 | AKR1C3 (0.49) | ALDH1A1POLBTDP1L3MBTL1APEX1 | |
| SCHEMBL5759739 | 0.78 | NOTUM (0.52) | ALDH1A1POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL1260315 | 0.77 | P2RX7 (0.42) | ALDH1A1POLBTDP1L3MBTL1APEX1 | |
| SCHEMBL4628972 | 0.75 | POLB (0.63) | ALDH1A1POLBTDP1L3MBTL1APEX1 | |
| SCHEMBL1259232 | 0.75 | ALDH1A1 (0.49) | ALDH1A1POLBTDP1L3MBTL1APEX1 | |
| SCHEMBL5755639 | 0.75 | CYP1A2 (0.48) | ALDH1A1POLBTDP1L3MBTL1MEN1 | |
| SCHEMBL5758300 | 0.73 | ALDH1A1 (0.50) | ALDH1A1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL20697505 | 0.72 | TSHR (0.47) | ALDH1A1POLBTDP1L3MBTL1APEX1 | |
| SCHEMBL17059031 | 0.71 | HSD17B10 (0.49) | ALDH1A1HSD17B10MEN1KMT2AMPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136663-A1 | FUSED HETEROCYCLIC DERIVATIVES AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-12 | — | — | WO | disclosed |