Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.46 |
| ▸ | ITGAV | P06756 | 1/20 | 0.46 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4629180 | 1.00 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2ITGB3ITGB1ITGAV | |
| SCHEMBL17923185 | 0.95 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2ITGB3ITGB1ITGAV | |
| SCHEMBL18040347 | 0.95 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2ITGB3ITGB1ITGAV | |
| SCHEMBL5688778 | 0.90 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2ITGB3ITGB1ITGAV | |
| SCHEMBL5688777 | 0.90 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2ITGB3ITGB1ITGAV | |
| SCHEMBL5688772 | 0.90 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2ITGB3ITGB1ITGAV | |
| SCHEMBL1802808 | 0.87 | ELANE (0.42) | ALDH1A1SMN1; SMN2ITGB3ITGB1ITGAV | |
| SCHEMBL10519057 | 0.87 | ELANE (0.42) | ALDH1A1SMN1; SMN2ITGB3ITGB1ITGAV | |
| SCHEMBL3486781 | 0.86 | KCNN4 (0.41) | ALDH1A1SMN1; SMN2ITGB3ITGB1ITGAV | |
| SCHEMBL31696763 | 0.83 | LTA4H (0.46) | ALDH1A1ITGB3ITGB1ITGAVITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116209438-A | Treatment of malignant diseases with SHP2 mutations using SOS1 inhibitors | 锐新医药公司 | 2023-06-02 | — | — | CN | disclosed |
| EP-1917234-A1 | TRITYLATION REACTIONS BASED ON METALLIC CATALYSIS | Universita'Degli Studi di Roma "La Sapienza" (IT) | 2008-05-07 | — | — | EP | disclosed |
| WO-2007009944-A1 | TRITYLATION REACTIONS BASED ON METALLIC CATALYSIS | Università degli Studi di Roma 'La Sapienza' (IT) | 2007-01-25 | — | — | WO | disclosed |
| EP-0801644-A4 | POLYARYLCARBAMOYLAZA -AND- CARBAMOYLALKANEDIOIC ACIDS | RHONE POULENC RORER PHARMA (US) | 2001-03-07 | — | — | EP | disclosed |
| EP-0801644-A1 | POLYARYLCARBAMOYLAZA -AND- CARBAMOYLALKANEDIOIC ACIDS | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1997-10-22 | — | — | EP | disclosed |
| US-5556990-A | SQUALENE SYNTHASE INHIBITORS, ANTICHOLESTEROL AGENTS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-09-17 | — | — | US | disclosed |
| WO-1996018615-A1 | POLYARYLCARBAMOYLAZA -AND- CARBAMOYLALKANEDIOIC ACIDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-06-20 | — | — | WO | disclosed |