Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 3/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4629178 | 0.86 | ALDH1A1 (0.48) | SMN1; SMN2CYP2C19ALDH1A1LMNACYP1A2 | |
| SCHEMBL4629180 | 0.86 | ALDH1A1 (0.48) | SMN1; SMN2CYP2C19ALDH1A1LMNACYP1A2 | |
| SCHEMBL18040347 | 0.82 | ALDH1A1 (0.43) | SMN1; SMN2CYP2C19ALDH1A1CHRM2CHRM4 | |
| SCHEMBL17923185 | 0.82 | ALDH1A1 (0.43) | SMN1; SMN2CYP2C19ALDH1A1CHRM2CHRM4 | |
| Acetic Acid SCHEMBL1572531 | 0.79 | LMNA (0.37) | KCNN4KCNA3SMN1; SMN2RAB9ACYP2C19 | |
| SCHEMBL5688778 | 0.77 | ALDH1A1 (0.40) | SMN1; SMN2ALDH1A1LMNACHRM2CHRM4 | |
| SCHEMBL5688777 | 0.77 | ALDH1A1 (0.40) | SMN1; SMN2ALDH1A1LMNACHRM2CHRM4 | |
| SCHEMBL5688772 | 0.77 | ALDH1A1 (0.40) | SMN1; SMN2ALDH1A1LMNACHRM2CHRM4 | |
| SCHEMBL1572532 | 0.77 | CHRNB2 (0.42) | SMN1; SMN2CYP2C19ALDH1A1MEN1SLC22A1 | |
| SCHEMBL1802808 | 0.75 | ELANE (0.42) | SMN1; SMN2ALDH1A1LMNACHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100035822-A1 | PROLINE-RICH PEPTIDES, PHARMACEUTICAL COMPOSITION, USE OF ONE OR MORE PEPTIDES AND METHOD OF TREATMENT | PEP FARMA CONSULTORIA E DESENVOLVIMENTO FARMACEUTI (BR) | 2010-02-11 | — | — | US | disclosed |