SCHEMBL46293

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Hydrochloric Acid SCHEMBL14892472	0.99	HDAC1 (0.51)	HDAC1HDAC6ENPP2HTR6HTR2A
	SCHEMBL6422248	0.84	HDAC1 (0.69)	HDAC1HDAC6HTR6HTR2AHTR2C
	SCHEMBL9615110	0.83	NPC1 (0.54)	HDAC1HDAC6HTR6HTR2AHTR2C
	SCHEMBL14963889	0.83	ALB (0.55)	HDAC1HDAC6HTR6HTR2AHTR2C
	Hydrochloric Acid SCHEMBL9615118	0.83	HDAC1 (0.67)	HDAC1HDAC6HTR6HTR2AHTR2C
	Hydrochloric Acid SCHEMBL9615105	0.82	KDM4E (0.53)	HDAC1HDAC6HTR6HTR2AHTR2C
	SCHEMBL4300297	0.81	HDAC1 (0.53)	HDAC1HDAC6HTR6HTR2AHTR2C
	SCHEMBL928866	0.79	HTR6 (0.52)	HDAC1HDAC6HTR6HTR2AHTR2C
	SCHEMBL18597484	0.79	ENPP2 (0.62)	HDAC1HDAC6ENPP2HTR6
	SCHEMBL12951709	0.78	HDAC6 (0.55)	HDAC1HDAC6HTR6HTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.