Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | TNKS | O95271 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17339930 | 0.86 | POLB (0.55) | ALDH1A1ALOX15BPOLBHDAC3CYP2C9 | |
| SCHEMBL5633461 | 0.81 | HDAC3 (0.62) | POLBHDAC3CYP2C9HDAC1HDAC6 | |
| SCHEMBL17288848 | 0.81 | CYP2C19 (0.73) | ALDH1A1ALOX15BPOLBCYP2C19HSD11B1 | |
| SCHEMBL2204217 | 0.80 | CYP2C19 (0.54) | ALDH1A1ALOX15BPOLBHDAC3CYP2C9 | |
| SCHEMBL13135854 | 0.79 | HTR4 (0.60) | ALDH1A1ALOX15BPOLBHDAC3CYP2C9 | |
| SCHEMBL16444566 | 0.78 | CA1 (0.56) | ALDH1A1ALOX15BPOLBHDAC3CYP2C9 | |
| SCHEMBL16456350 | 0.78 | ALDH1A1 (0.56) | ALDH1A1ALOX15BPOLBHDAC3CYP2C9 | |
| SCHEMBL407300 | 0.78 | CYP2C19 (0.53) | ALDH1A1ALOX15BHDAC3CYP2C9HDAC1 | |
| SCHEMBL15289091 | 0.78 | CA1 (0.56) | ALDH1A1ALOX15BPOLBHDAC3CYP2C9 | |
| SCHEMBL16455988 | 0.78 | ALDH1A1 (0.56) | ALDH1A1ALOX15BPOLBHDAC3CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065196-A1 | AMIDE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-15 | — | — | US | disclosed |
| WO-2008011130-A2 | AMIDE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065196-A1 | AMIDE COMPOUNDS | DGAT2, DGAT1, DLAT | ALDH1A1 272/4885ALOX15B 603/4885POLB 2752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.