Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 6/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | ITK | Q08881 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | HTR1D | P28221 | 2/20 | 0.39 |
| ▸ | HTR1B | P28222 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4630173 | 0.92 | HRH4 (0.45) | POLBHTR6HRH4HTR2CHTR2A | |
| SCHEMBL4629732 | 0.83 | CYP3A4 (0.46) | POLBHRH4HTR2CITKHTR2A | |
| SCHEMBL4629706 | 0.83 | HTR6 (0.45) | POLBHTR6HRH4HTR2CHTR2A | |
| SCHEMBL4629545 | 0.82 | VCP (0.47) | HTR6HRH4HTR2CHTR2A | |
| SCHEMBL4630178 | 0.82 | HTR6 (0.44) | POLBHTR6HRH4ITKHTR2A | |
| Hydrochloric Acid SCHEMBL4628914 | 0.82 | VCP (0.46) | HTR6HRH4HTR2CHTR2AHTR1A | |
| SCHEMBL4630016 | 0.82 | CA2 (0.46) | HTR6HRH4HTTCNR1HRH3 | |
| SCHEMBL16986603 | 0.80 | POLB (0.44) | POLBHTR6HTR2CHTR2AHTR1A | |
| SCHEMBL4630008 | 0.79 | HTR6 (0.42) | HTR6HRH4ITKLMNAHRH3 | |
| Hydrochloric Acid SCHEMBL2225211 | 0.79 | HTR6 (0.43) | POLBHTR6HTR2CHTR2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919896-A1 | AMINOARYL SULPHONAMIDE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS. | Suven Life Sciences Limited (IN) | 2008-05-14 | — | — | EP | claimed |
| WO-2007020652-A1 | AMINOARYL SULPHONAMIDE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS. | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | claimed |