Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.52 |
| ▸ | FEN1 | P39748 | 1/20 | 0.52 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4629540 | 0.98 | ALOX5AP (0.50) | ALOX5APFEN1SOAT1EPHX2PTPN1 | |
| SCHEMBL2703944 | 0.93 | ALOX5AP (0.46) | ALOX5APFEN1SOAT1PTPN1 | |
| SCHEMBL2704545 | 0.86 | ALOX5AP (0.48) | ALOX5APFEN1 | |
| SCHEMBL7603506 | 0.82 | KDM4E (0.38) | ALOX5APFEN1 | |
| SCHEMBL7208440 | 0.81 | CA2 (0.44) | ALOX5APFEN1 | |
| SCHEMBL2445897 | 0.81 | ALOX5AP (0.47) | ALOX5APFEN1 | |
| SCHEMBL5592399 | 0.81 | APEX1 (0.47) | — | |
| SCHEMBL2704655 | 0.81 | PSIP1 (0.50) | ALOX5APFEN1 | |
| SCHEMBL8997320 | 0.80 | HDAC1 (0.45) | ALOX5APFEN1SOAT1MMP9 | |
| SCHEMBL29700187 | 0.80 | PGAM1 (0.42) | ALOX5APFEN1SOAT1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919907-A2 | HETEROCYCLIC COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007026959-A2 | DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZ0 [B] THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-03-08 | — | — | WO | disclosed |
| CN-1155095-A | Photo-electric modulator | NAMOURS DU PONT CO (US) | 1997-07-23 | — | — | CN | disclosed |
| CN-1141441-A | Optical device for frequency conversion | DU PONT (US) | 1997-01-29 | — | — | CN | disclosed |
| CN-1054587-A | Fluorinated sulfones/ketones for nonlinear optics | DU PONT (US) | 1991-09-18 | — | — | CN | disclosed |