SCHEMBL4630201

SCHEMBL4630201

Nc1ccc2ccccc2c1[O]

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
HSD17B10 Q99714 3/20 0.52
TSHR P16473 3/20 0.52
CYP3A4 P08684 1/20 0.52
HPGD P15428 1/20 0.52
KEAP1 Q14145 1/20 0.52
CYP2A6 P11509 3/20 0.50
TDP1 Q9NUW8 1/20 0.50
HPRT1 P00492 2/20 0.48
PAX8 Q06710 1/20 0.43
HIF1A Q16665 1/20 0.42
CYP1B1 Q16678 1/20 0.42
F12 P00748 1/20 0.40
PLAU P00749 1/20 0.40
NCF1 P14598 1/20 0.40
NOS3 P29474 1/20 0.40
NOS1 P29475 1/20 0.40
NOS2 P35228 1/20 0.40
BACE1 P56817 1/20 0.40
CA1 P00915 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31390038 0.75 ALDH1A1 (0.56) ALDH1A1HSD17B10TSHRCYP3A4HPGD
1,2-Naphthoquinone SCHEMBL2146624 0.75 ALDH1A1 (0.55) ALDH1A1HSD17B10TSHRCYP3A4HPGD
SCHEMBL29418178 0.75 ALDH1A1 (0.56) ALDH1A1HSD17B10TSHRCYP3A4HPGD
SCHEMBL455943 0.75 ALDH1A1 (0.56) ALDH1A1HSD17B10TSHRCYP3A4HPGD
SCHEMBL64806 0.75 ALDH1A1 (0.56) ALDH1A1HSD17B10TSHRCYP3A4HPGD
Formaldehyde SCHEMBL28941694 0.74 ALDH1A1 (0.50) ALDH1A1HSD17B10TSHRCYP3A4HPGD
Hydrochloric Acid SCHEMBL31439257 0.73 ALDH1A1 (0.54) ALDH1A1HSD17B10TSHRCYP3A4HPGD
SCHEMBL31633515 0.73 ALDH1A1 (0.54) ALDH1A1HSD17B10TSHRCYP3A4HPGD
SCHEMBL31633516 0.73 ALDH1A1 (0.54) ALDH1A1HSD17B10TSHRCYP3A4HPGD
Hydrochloric Acid SCHEMBL430346 0.73 ALDH1A1 (0.54) ALDH1A1HSD17B10TSHRCYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10745372-B2 Compound, resin, material for forming underlayer film for lithography, underlayer film for lithography, pattern forming method, and purification method MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2020-08-18 US claimed
JP-1027648-A None JP disclosed
US-10745372-B2 Compound, resin, material for forming underlayer film for lithography, underlayer film for lithography, pattern forming method, and purification method MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2020-08-18 US disclosed
US-20180029968-A1 COMPOUND, RESIN, MATERIAL FOR FORMING UNDERLAYER FILM FOR LITHOGRAPHY, COMPOSITION FOR FORMING UNDERLAYER FILM FOR LITHOGRAPHY, UNDERLAYER FILM FOR LITHOGRAPHY, RESIST PATTERN FORMING METHOD, CIRCUIT PATTERN FORMING METHOD, AND PURIFICATION METHOD OF COMPOUND OR RESIN MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2018-02-01 US disclosed
EP-3257835-A1 COMPOUND, RESIN, LITHOGRAPHY UNDERLAYER FILM FORMING MATERIAL, LITHOGRAPHY UNDERLAYER FILM FORMING COMPOSITION, LITHOGRAPHY UNDERLAYER FILM, METHOD FOR FORMING RESIST PATTERN, METHOD FOR FORMING CIRCUIT PATTERN, AND METHOD FOR PURIFYING COMPOUND OR RESIN Mitsubishi Gas Chemical Company, Inc. (JP) 2017-12-20 EP disclosed
US-20170349564-A1 COMPOUND, RESIN, MATERIAL FOR FORMING UNDERLAYER FILM FOR LITHOGRAPHY, UNDERLAYER FILM FOR LITHOGRAPHY, PATTERN FORMING METHOD, AND PURIFICATION METHOD MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2017-12-07 US disclosed
EP-3239141-A1 COMPOUND, RESIN, UNDERLAYER FILM FORMING MATERIAL FOR LITHOGRAPHY, UNDERLAYER FILM FOR LITHOGRAPHY, PATTERN FORMING METHOD AND PURIFICATION METHOD Mitsubishi Gas Chemical Company, Inc. (JP) 2017-11-01 EP disclosed
CN-103476745-B Diamine compound containing sulfonic acid group and method for producing same NITTO DENKO CORP. (JP) 2015-09-30 CN disclosed
CN-102341701-B Mimetics of normal fresh platelets BIO RAD LABORATORIES 2014-07-09 CN disclosed
CN-103476832-A Polyimide, polyimide polymer electrolyte membrane, membrane electrode assembly, and solid polymer fuel cell NITTO DENKO CORP 2013-12-25 CN disclosed
CN-101258147-B 4-piperazin-1-yl-4-benzo [ B ] thiophene derivatives for the treatment of CNS disorders OTSUKA PHARMA CO LTD 2012-03-21 CN disclosed
CN-102341701-A Mimetics of normal fresh platelets BIO RAD LABORATORIES 2012-02-01 CN disclosed
CN-101868563-A Base processing agent for metal material and method for processing base for metal material NIHON PARKERIZING 2010-10-20 CN disclosed
CN-101258147-A 4-piperazin-1-yl-4-benzo [ B ] thiophene derivatives for the treatment of CNS disorders OTSUKA PHARMA CO LTD (JP) 2008-09-03 CN disclosed
EP-1919907-A2 HETEROCYCLIC COMPOUND OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2008-05-14 EP disclosed
WO-2007026959-A2 DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZ0 [B] THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-03-08 WO disclosed
US-6057336-A ANTIINFLAMMATORY AGENTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2000-05-02 US disclosed
US-5629406-A AMINO ACID DERIVATIVES SANKYO COMPANY, LIMITED (JP) 1997-05-13 US disclosed
EP-0587311-A1 Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use SANKYO COMPANY LIMITED (JP) 1994-03-16 EP disclosed
JP-S6427648-A METHOD OF REFINING ALKALINE SOLUTION SUMITOMO CHEMICAL CO 1989-01-30 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170349564-A1 COMPOUND, RESIN, MATERIAL FOR FORMING UNDERLAYER FILM FOR LITHOGRAPHY, UNDERLAYER FILM FOR LITHOGRAPHY, PATTERN FORMING METHOD, AND PURIFICATION METHOD ASH2L, MLLT1, FRG1 ALDH1A1 1912/4885HSD17B10 1750/4885TSHR 3984/4885
US-20180029968-A1 COMPOUND, RESIN, MATERIAL FOR FORMING UNDERLAYER FILM FOR LITHOGRAPHY, COMPOSITION FOR FORMING UNDERLAYER FILM FOR LITHOGRAPHY, UNDERLAYER FILM FOR LITHOGRAPHY, RESIST PATTERN FORMING METHOD, CIRCUIT PATTERN FORMING METHOD, AND PURIFICATION METHOD OF COMPOUND OR RESIN PRMT9, ARGLU1, MLLT1 ALDH1A1 1309/4885HSD17B10 3367/4885TSHR 2806/4885
US-10745372-B2 Compound, resin, material for forming underlayer film for lithography, underlayer film for lithography, pattern forming method, and purification method ASH2L, MLLT1, FRG1 ALDH1A1 1912/4885HSD17B10 1750/4885TSHR 3984/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.