SCHEMBL318448

SCHEMBL318448

Cc1cc(N)c2ccccc2c1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 1.00
HTT P42858 4/20 0.63
LMNA P02545 3/20 0.63
KDM4E B2RXH2 3/20 0.45
MAPT P10636 2/20 0.45
GAA P10253 2/20 0.45
ALDH1A1 P00352 2/20 0.45
HDAC3 O15379 1/20 0.45
IDO1 P14902 1/20 0.45
EP300 Q09472 1/20 0.45
KAT2B Q92831 1/20 0.45
KAT8 Q9H7Z6 1/20 0.45
NCOR2 Q9Y618 1/20 0.45
NCF1 P14598 1/20 0.42
HPRT1 P00492 1/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
MEN1 O00255 1/20 0.41
MAPK1 P28482 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2148941 0.98 PKM (0.96) PKMHTTLMNAKDM4EMAPT
Hydrochloric Acid SCHEMBL1651218 0.96 PKM (0.92) PKMHTTLMNAKDM4EMAPT
SCHEMBL11583446 0.83 PKM (0.70) PKMHTTLMNAKDM4EMAPT
SCHEMBL31634598 0.79 PKM (0.65) PKMHTTLMNAKDM4EMAPT
SCHEMBL7191579 0.79 PKM (0.65) PKMHTTLMNAKDM4EMAPT
SCHEMBL10579123 0.79 HTT (0.71) PKMHTTLMNAKDM4EMAPT
SCHEMBL4630376 0.79 HTT (0.71) PKMHTTLMNAKDM4EMAPT
SCHEMBL352532 0.77 PKM (0.63) PKMHTTLMNAKDM4EMAPT
SCHEMBL31517208 0.77 PKM (0.63) PKMHTTLMNAKDM4EMAPT
SCHEMBL10712402 0.77 PKM (0.63) PKMHTTLMNAKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 503 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250345289-A1 NANO-PARTICLES OF MENAQUINONE AND METHODS OF TREATMENT EPIZON INC (US) 2025-11-13 US claimed
US-20250339386-A1 VITAMIN K2 FOR USE IN TREATMENT OF CORONARY ARTERY CALCIFICATION REGION SYDDANMARK (DK) 2025-11-06 US claimed
EP-3938040-B1 VITAMIN K2 IN COMBINATION WITH ANTICOAGULANTS FOR USE IN TREATING MUSCLE SORENESS LESAFFRE & CIE (FR) 2025-05-21 EP claimed
EP-4531825-A1 VITAMIN K2 FOR USE IN TREATMENT OF CORONARY ARTERY CALCIFICATION Region Syddanmark (DK) 2025-04-09 EP claimed
WO-2025011276-A1 GLYCOPEPTIDE MOLECULE 粤港澳大湾区精准医学研究院(广州) 2025-01-16 WO claimed
CN-119306802-A Glycopeptide molecule 粤港澳大湾区精准医学研究院(广州) 2025-01-14 CN claimed
CN-119300813-A Vitamin K2 for the treatment of Coronary Artery Calcification (CAC) 南丹麦大区 2025-01-10 CN claimed
CN-118926753-A Modularized construction method of dry moving bed desulfurizing tower 中化二建集团有限公司 2024-11-12 CN claimed
US-20240307321-A1 NANO-PARTICLES OF MENAQUINONE AND METHODS OF TREATMENT Epizon Pharma, Inc. (US) 2024-09-19 US claimed
WO-2024177973-A1 NANO-PARTICLES OF MENAQUINONE AND METHODS OF TREATMENT Epizon Pharma, Inc. (US) 2024-08-29 WO claimed
US-20220233629-A1 COMPOSITION COMPRISING LIDOCAINE, L-CARNOSINE AND DEXPANTHENOL CELLIX BIO PRIVATE LIMITED (IN) 2022-07-28 US claimed
WO-2022157587-A1 A COMPOSITION COMPRISING LIDOCAINE, L-CARNOSINE AND DEXPANTHENOL CELLIX BIO PRIVATE LIMITED (IN) 2022-07-28 WO claimed
US-11289345-B2 Heat releasing semiconductor chip package and method for manufacturing the same MAGNACHIP SEMICONDUCTOR, LTD. (KR) 2022-03-29 US claimed
CN-114231554-A Vitamin k2Biosynthesis method of series products 安徽工程大学 2022-03-25 CN claimed
US-20150283290-A1 STERILIZED COMPOSITIONS OF CYANOACRYLATE MONOMERS AND NAPHTHOQUINONE 2,3-OXIDES ADHEZION BIOMEDICAL, LLC (US) 2015-10-08 US claimed
CN-103025338-B Composition for improving condition of skin MEIJI CO LTD 2015-01-28 CN claimed
CN-103025338-A Composition for improving condition of skin MEIJI CO LTD 2013-04-03 CN claimed
US-20090281187-A1 ANTI-ALLERGIC AGENT MEIJI DAIRIES CORP (JP) 2009-11-12 US claimed
CN-101247800-A Antiallergic agent MEIJI DAIRIES CORP (JP) 2008-08-20 CN claimed
EP-1946752-A1 ANTI-ALLERGIC AGENT Meiji Dairies Corporation (JP) 2008-07-23 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240307321-A1 NANO-PARTICLES OF MENAQUINONE AND METHODS OF TREATMENT PROC, NDUFS6, NDUFS3 PKM 596/4885HTT 2863/4885LMNA 639/4885
US-20250345289-A1 NANO-PARTICLES OF MENAQUINONE AND METHODS OF TREATMENT PROC, NDUFS6, NDUFS3 PKM 596/4885HTT 2863/4885LMNA 639/4885
US-20220233629-A1 COMPOSITION COMPRISING LIDOCAINE, L-CARNOSINE AND DEXPANTHENOL VNN1, LPL, HMGB1 PKM 2064/4885HTT 786/4885LMNA 16/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.