Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 6/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 6/20 | 0.33 |
| ▸ | PARP1 | P09874 | 5/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL454917 | 0.80 | TNKS (0.41) | TNKSTNKS2PARP1GRIN1GRIN2B | |
| SCHEMBL9903971 | 0.67 | CYP1A2 (0.40) | GRIN1GRIN2B | |
| SCHEMBL3234904 | 0.61 | IRAK4 (0.31) | — | |
| SCHEMBL13291364 | 0.61 | HSD11B1 (0.32) | — | |
| SCHEMBL454863 | 0.61 | WNT3A (0.39) | TNKS2 | |
| SCHEMBL13291842 | 0.61 | TRPV1 (0.36) | KCNH2 | |
| SCHEMBL13291801 | 0.60 | TRPV1 (0.32) | — | |
| SCHEMBL13291798 | 0.60 | TRPV1 (0.32) | — | |
| SCHEMBL30177122 | 0.59 | DRD2 (0.32) | KCNH2 | |
| SCHEMBL13383746 | 0.58 | TRPV1 (0.32) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2475654-A1 | HERBICIDAL PYRIMIDONE DERIVATIVES | E. I. du Pont de Nemours and Company (US) | 2012-07-18 | — | — | EP | disclosed |
| WO-2012033548-A2 | HERBICIDAL BIS-NITROGEN-CONTAINING OXO AND SULFONO HETEROCYCLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-15 | — | — | WO | disclosed |
| WO-2011031658-A1 | HERBICIDAL PYRIMIDONE DERIVATIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-03-17 | — | — | WO | disclosed |