SCHEMBL4631140

SCHEMBL4631140

Oc1ccc(-c2ccc3c(c2-c2ccc(O)c(-c4ccccc4)c2)Cc2ccccc2-3)cc1-c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 2/20 0.41
HSD17B1 P14061 1/20 0.40
HSD17B2 P37059 1/20 0.40
ALDH1A1 P00352 2/20 0.40
HPGD P15428 2/20 0.40
BCL2L1 Q07817 1/20 0.40
HSD17B10 Q99714 1/20 0.40
PNMT P11086 1/20 0.38
APP P05067 1/20 0.38
ADORA2A P29274 1/20 0.38
ADORA1 P30542 1/20 0.38
SRD5A2 P31213 1/20 0.37
ALOX5 P09917 2/20 0.37
PGR P06401 1/20 0.36
PELI1 Q96FA3 1/20 0.35
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
KDR P35968 1/20 0.35
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21224075 0.89 HSD17B1 (0.43) BACE1HSD17B1HSD17B2ALDH1A1HPGD
SCHEMBL30036609 0.87 APP (0.53) ALDH1A1HPGDPNMTAPPSRD5A2
SCHEMBL28847551 0.87 APP (0.53) ALDH1A1HPGDPNMTAPPSRD5A2
SCHEMBL3366835 0.87 HSD17B1 (0.47) BACE1HSD17B1HSD17B2ALDH1A1HPGD
SCHEMBL5717486 0.83 TLR8 (0.42) HSD17B1HSD17B2ALDH1A1HPGDPNMT
SCHEMBL29800533 0.83 HPGD (0.45) ALDH1A1HPGDHSD17B10PNMTAPP
SCHEMBL30314491 0.83 TLR8 (0.42) HSD17B1HSD17B2ALDH1A1HPGDPNMT
SCHEMBL29921844 0.83 TLR8 (0.42) HSD17B1HSD17B2ALDH1A1HPGDPNMT
SCHEMBL1372572 0.83 HPGD (0.45) ALDH1A1HPGDHSD17B10PNMTAPP
SCHEMBL30385603 0.83 PNMT (0.38) ALDH1A1HPGDPNMTAPPADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019194111-A1 POLYMER FOR RETARDATION FILM, RETARDATION FILM, AND MANUFACTURING METHOD AND USE THEREOF 大阪ガスケミカル株式会社 2019-10-10 WO disclosed
EP-1613985-B1 OPTICAL FILMS COMPRISING ONE OR MORE POLYARYLATES OBTAINED FROM SPECIFIC PHENOLIC MOLECULES FERRANIA TECHNOLOGIES SPA (IT) 2008-05-14 EP disclosed